Influence of Extraction Time on the Yield, Chemical Composition, and Antibacterial Activity of the Essential Oil from Origanum elongatum (E. & M.) Harvested at Northern Morocco

Phytochemistry, Toxicology, and Pharmacological Properties of Origanum elongatum

“…On the other hand, a previous study [4] showed that the chemical profile of O. elongatum EO shows the predominance of oxygenated compounds (65.14%), followed by hydrocarbon compounds (28.02%), knowing that thymol is the major compound with 63.44%. ese results confirm the findings of [5], which showed that the main constituents found in the aerial parts of O. elongatum EO are carvacrol (67.34%), c-terpinene (3.29%), p-cymene (3.62%), and thymol (1.79%).…”

“…e DVF was active against all the studied bacteria; the strongest effect was observed on B. subtilis DCM 6633 with a large inhibition zone (41.0 ± 2.6 mm). Also, the total EO of O. elongatum was highly active against S. aureus ATCC 25923, B. subtilis DCM 6633, and E. coli ATCC 25922, with inhibition zones ranging from 21.3 to 24.6 mm, while a moderate effect was observed against E. coli K12 [4].…”

“…Several studies showed the antibacterial efficacy of different EOs or extracts from different O. elongatum parts [3,4,6,[9][10][11]. Table 2 summarizes all the studies evaluating the antimicrobial activity of O. elongatum extracts and EOs.…”

“…Phytochemical investigations showed that O. elongatum contains several classes of bioactive compounds, including terpenoids, flavonoids, oxygenated compounds, hydrocarbon compounds, and phenolic compounds [1][2][3][4][5][6][7][8]. e main volatile compounds of this species are carvacrol, thymol, linalool, and limonene.…”

“…Pharmacological reports showed that extracts and essential oils (EOs) of O. elongatum exhibited various biological activities such as antibacterial [3,4,6,[9][10][11], antifungal [3,12], antiparasitic [5,[13][14][15][16], antiviral [6], antioxidant [1], vasodilator [10,17], corrosion inhibitor [18], and hepatoprotective effects [19]. ese biological effects are certainly due to the chemical composition of O. elongatum, in particular the main compounds such as carvacrol, linalool, and thymol.…”