Influence of Encapsulated Aroma Compounds on the Formation and Morphology of Gelatin Microparticles

Abstract

In the present work aromatic essential oils obtained from orange (OO), basil (BO), cinnamon (CNO), and citronella (CO) were encapsulated in natural gelatin matrices through inverse suspension processes and the effects of oil encapsulation on the formation and morphology of the obtained gelatin microspheres were analyzed. Particularly, it is shown that each oil affected the course of the encapsulation process differently, leading to decrease of the viscosity of the dispersed phase of almost 70% during the reaction course, when compared with oil‐free gelatin solutions. Additionally, the interfacial tensions of the aqueous solutions containing essential oils were slightly higher than in absence of oils. Particle size distributions of the final particles were relatively broad, while the obtained beads presented spherical morphology and irregular surfaces. Finally, the thermal resistances of the oil‐containing microparticles were higher than observed in absence of oil, despite the relatively low oil contents of the final products.

Recent advances in the formulation of PLGA microparticles for controlled drug delivery

“…In particular, MPs can be used for the controlled release of drugs (Choi et al 2011 ; Guo et al 2015 ) that can be modulated by choosing the kind of polymer and its chemical and molecular features such as molecular weight (MW), monomer composition (Takeuchi et al 2017 ), crystallinity, glass transition temperature ( T g ), and inherent viscosity (Ansary et al 2014 ). In this scenario, a lot of biodegradable polymers can be used to formulate MPs as alginate (Strobel et al 2020 ), dextran (Shah et al 2019 ), chitosan (Batista et al 2019 ), gelatin (da Silva and Pinto et al 2019 ) and poly-(lactic- co -glycolic acid) (PLGA) (Kapoor et al 2015 ). These polymers are preferred, because their degradation products are non-toxic metabolites and are also easily eliminated (Makadia and Siegel 2011 ).…”

Microdesigned Nanocellulose-Based Flexible Antibacterial Aerogel Architectures Impregnated with Bioactive Cinnamomum cassia

“…Due to the presence of various components, numerous bands appeared in the spectra with the overlap of each absorption spectrum of various compounds present in ci E. Importantly, the band at 1726 cm –1 corresponds to the aldehyde of saturated fat. The bands at 1679 and 1625 cm –1 represent the stretching vibration of the CO groups of aldehydes. , These bands appeared wider as compared to a typical aldehyde compound due to the influence of conjugation and the aromatic ring and revealed the high level of cinnamaldehyde and aldehydes in ci E. , The strong absorption bands between 1000–687 cm –1 indicated the presence of aromatic CC bonds, which are specifically associated with cinnamaldehyde present in ci E. , Hence, both the FTIR and GC–MS analysis of ci E substantiate the adequate extraction of cinnamaldehyde, as the key constituent, from cinnamon bark powder. A detailed summary of the various other characteristic bands observed in the FTIR spectra of ci E has been presented in Table S3 of the Supporting Information.…”