Uterine artery embolization (UAE) has been widely used for a number of years as an alternative mini-invasive method of treatment of symptomatic uterine fibroids. The technical aspects of the UFE are described in sufficient detail in various guidelines, recommendations and scientific articles. Along with low trauma and other benefits, UAE, like any other treatment, can be accompanied by some intra- and postinterventional complications. One of the intraoperative complications is uterine artery spasm. In most cases the spasm is eliminated medically and is considered to be a temporary and reverse phenomenon. Persistent spasm of the uterine artery can really prevent the adequate embolization of perifibroid arteries and subsequently cause ineffective treatment. The article provides a case of persistent spasm of the uterine artery at the final stage of its embolization for uterine leiomyoma. A set of intraoperative measures to eliminate this complication is described, which, in the end, allowed to properly complete the intervention. Keywords: Uterine fibroids, uterine artery embolization, complications, spasm of the uterine artery.