Influence of early life exposures on incidence and remission of asthma throughout life☆

Marco, Roberto de; Pattaro, Cristian; Locatelli, Francesca; Svanes, Cecilie

doi:10.1016/j.jaci.2004.01.780

Cited by 93 publications

(82 citation statements)

References 41 publications

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“…One such factor with CRD is a family history of CRD. This is consistent with the fi ndings of Ronchetti et al (29) and De Marco et al (30). They have both found that a family history of asthma or allergy is associated with a higher risk of developing asthma in children.…”

Section: Discussionsupporting

confidence: 91%

A Prevalence Study on Outdoor Air Pollution and Respiratory Diseases in Children in Zasavje, Slovenia, as a Lever to Trigger Evidence-based Environmental Health Activities

Kukec

Farkaš

Eržen

et al. 2013

Archives of Industrial Hygiene and Toxicology

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The aim of this study was to estimate the population burden of respiratory diseases in the Zasavje region of Slovenia that can be attributed to outdoor air pollution in order to gain relevant grounds for evidencebased public health activities. In 2008, 981 schoolchildren (age 6 to 12 years) were observed in a prevalence study. The prevalence of chronic respiratory diseases (CRD) and frequent acute respiratory symptoms (FARS) was related to the level of outdoor air pollution in the local environment (low, moderate and high pollution areas). Logistic regression was used as a method for statistical analysis. The prevalence of CRD was 3.0 % in low pollution areas, 7.5 % in moderate pollution areas, and 9.7 % in high pollution areas (p=0.005). After adjustment for the effects of confounders, 2.91-times higher odds for CRD were registered in high pollution areas in comparison to low pollution areas (p=0.017). The prevalence of FARS was: 7.8 % in low pollution areas, 13.3 % in moderate pollution areas and 15.9 % in high pollution areas (p=0.010). After adjustment for the effects of confounders, 2.02-times higher odds for FARS were registered in high pollution areas in comparison to low pollution areas (p=0.023). The study confi rmed a signifi cantly higher prevalence of CRD and FARS in children living in high pollution areas of Zasavje. These results at least partially prompted mutual understanding and cross-sectoral cooperation -prerequisites for solving complex problems involving the impact of air pollution on health.

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Section: Discussionsupporting

confidence: 91%

A Prevalence Study on Outdoor Air Pollution and Respiratory Diseases in Children in Zasavje, Slovenia, as a Lever to Trigger Evidence-based Environmental Health Activities

Kukec

Farkaš

Eržen

et al. 2013

Archives of Industrial Hygiene and Toxicology

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“…These cutoff points were chosen to be as consistent as possible with previously published definitions. 13 Age at onset of asthma. This was self-reported in the 2004 survey.…”

Section: Definitionsmentioning

confidence: 99%

Childhood allergic rhinitis predicts asthma incidence and persistence to middle age: A longitudinal study

Burgess

Walters

Byrnes

et al. 2007

Journal of Allergy and Clinical Immunology

201

131

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“…While the prevalence of asthma and nasal allergy has been reported previously in adult German populations [7,8], there are no studies providing incidence rates for Germany utilising a long-term follow-up of 20 years. Previous studies [3,4,9,10] have identified sex, smoking, atopy, body mass index, bronchial hyperresponsiveness (BHR), exposure to mould and early acute respiratory infection as risk factors for asthma and nasal allergy. However, no study has considered the potential predictive value of skin prick tests (SPTs) or radioallergosorbent tests (RASTs) as determinants for new asthma and nasal allergy onset in adults.…”

Section: Introductionmentioning

confidence: 99%

Prediction of new-onset asthma and nasal allergy by skin prick test and RAST in a cohort of adults

Gallmeier

Becker

Kirsten

et al. 2013

European Respiratory Journal

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Limited information exists regarding the incidence and predictors of asthma and nasal allergy in adulthood. We determined the incidence rate of asthma and nasal allergy in adults and assessed the predictive value of skin prick tests (SPTs) and radioallergosorbent tests (RASTs) for these two outcomes.Two German centres involved in the European Community Respiratory Health Survey conducted a follow-up assessment in 2012 of the baseline participants (1185 adults aged 21-47 years assessed in 1990). The predictive value of SPTs and RASTs on new-onset asthma and nasal allergy was assessed by Cox regression and by calculating the positive or negative predictive value.During the 20 years between baseline and follow-up, 3.1 and 4.4 per 1000 person-years of new-onset asthma and nasal allergy cases were recorded, respectively. The hazard ratios for SPTs of any specific and of all aeroallergens combined were slightly higher than those of RASTs for asthma and nasal allergy. The negative predictive values of both the SPT and RAST were very high and similar (0.94-0.96), whereas the postive predictive values were low (0.09-0.20).Positive SPT results showed a better association with new onset asthma and nasal allergy than positive RAST either to any specific aeroallergens or to all combined. @ERSpublications Positive SPT shows better association with new-onset asthma and nasal allergy than positive radioallergosorbent tests

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Influence of early life exposures on incidence and remission of asthma throughout life☆

Cited by 93 publications

References 41 publications

A Prevalence Study on Outdoor Air Pollution and Respiratory Diseases in Children in Zasavje, Slovenia, as a Lever to Trigger Evidence-based Environmental Health Activities

A Prevalence Study on Outdoor Air Pollution and Respiratory Diseases in Children in Zasavje, Slovenia, as a Lever to Trigger Evidence-based Environmental Health Activities

Childhood allergic rhinitis predicts asthma incidence and persistence to middle age: A longitudinal study

Prediction of new-onset asthma and nasal allergy by skin prick test and RAST in a cohort of adults

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