Influence of dimethyl sulfoxide used as a solvent on the physical properties and long-term dentin bonding of hydrophilic resins

Stape, Thiago Henrique Scarabello; Tezvergil‐Mutluay, Arzu; Mutluay, Mustafa Murat; Martins, Luís Roberto Marcondes; Prado, Rosana Leal do; Pizi, Eliane Cristina Gava; Tjäderhane, Leo

doi:10.1016/j.jmbbm.2016.07.003

Cited by 25 publications

(23 citation statements)

References 39 publications

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“…It also possesses the polarity needed to break down water's self-association and forms stable complexes with water to create "hydrophobic water" [183,184]. Recent studies have shown increase both in immediate and long-term bond strength [185,181,[186][187][188]. The increase in immediate bod strength may be due to DMSOinduced improvement in dentin wettability [189], which may be the reason for the better adhesive penetration [181].…”

Section: Removal Of the Unbound/residual Water Within The Hlmentioning

confidence: 99%

Dentin bonding systems: From dentin collagen structure to bond preservation and clinical applications

et al. 2018

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Section: Removal Of the Unbound/residual Water Within The Hlmentioning

confidence: 99%

Dentin bonding systems: From dentin collagen structure to bond preservation and clinical applications

et al. 2018

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“…The transport of oral fluids (saliva, organic acids produced by the oral biofilm and water) through the adhesive polymer structure is crucial to the degradation of the tooth-adhesive interfaces [ 3 , 38 , 39 ], and this has been related to the impairment of some physical properties of the adhesive systems [ 40 ]. Thus, the evaluation of water sorption and solubility is crucial to analyze the performance of innovative-bioactive adhesive systems [ 17 , 41 ]. In the current study, the experimental adhesive system with 2 wt.% of ZnCl 2 did not suffer higher water sorption and solubility than the model blend Zn0 (control).…”

Section: Discussionmentioning

confidence: 99%

ZnCl₂ Incorporated into Experimental Adhesives: Selected Physicochemical Properties and Resin-Dentin Bonding Stability

Almeida

Silva

Guimarães

et al. 2017

BioMed Research International

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The aim of this study was to evaluate the degree of conversion (DC%), water sorption (WS), solubility (SO), and resin-dentin bonding stability of experimental adhesive systems containing ZnCl2. Different concentrations (wt.%) of ZnCl2 were added to a model etch-and-rinse adhesive system consisting of BISGMA, HEMA, UDMA, GDMA, water, and ethanol: Zn0 (0%-control group); Zn2 (2%); Zn3.5 (3.5%); and Zn5 (5%). Adper Single Bond 2 (SB) was used as commercial reference. The samples were light cured for 20s using a quartz-tungsten-halogen unit (650 mW/cm2). DC% (n = 5) was measured using FT-IR spectroscopy, and WS and SO (n = 5) were calculated based on ISO4049. Microtensile bond strength (μTBS) and nanoleakage (NL) were measured after 24 h and 12 months of water storage (n = 10). Data were analyzed using ANOVA and Tukey's HSD test (5%). Zn5 presented the lowest DC% and the highest WS and SO (p < 0.05). Zn0 and Zn2 presented statistically similar DC%, WS, SO, and immediate μTBS. All adhesives containing ZnCl2 maintained a μTBS stability after 12 months, but only Zn2 and Zn3.5 did not suffer an increase in NL. SB presented the highest immediate μTBS but the greatest reduction after 12 months (p < 0.05). The addition of 2 wt.% of ZnCl2 in adhesive formulations seems to be a promising way to improve the resin-dentin bonding stability. Higher concentrations than 2 wt.% could impair some physicochemical properties.

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“…Although DMSO was originally proposed as a potential solvent to simplify the reaction of polymerization in adhesive applications [16], only recently several in vitro studies have shown that DMSO pretreatment of dentin can improve the immediate and long-term dentin bond strength and lower long term nanoleakeage from relatively low (0004%) to high concentrations (50%) [17][18][19][20][21][22][23][24]. Enhanced monomer penetration into the collagen matrix [18,21] has been suggested as a possible mechanism but no systematic information is available regarding the effect of DMSO on adhesive monomer penetration.…”

Section: Introductionmentioning

confidence: 99%

Influence of polar solvents on permeability, stiffness and collagen dissociation of demineralized dentin

Al-Ani

Mutluay

Tjäderhane

et al. 2019

International Journal of Adhesion and Adhesives

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The purpose of this in vitro study was to evaluate and compare the effect of dimethyl sulfoxide (DMSO) or ethanol on the permeability, stiffness and collagen dissociation of demineralized dentin. Dentin cubes (2 × 2 × 2 mm) were demineralized in EDTA and incubated in DMSO or ethanol (0.01, 0.1, 1, 5, 10, 20, 50 and 100%) (n= 10/group) for 30 s, followed by 100% HEMA incubation. Extracted HEMA was quantified. For elastic modulus (E), demineralized dentin beams (6 × 2 × 1 mm) were incubated in DMSO or ethanol (1, 10, 20, 50 and 100%) for 10, 30 or 60 min at 3-point bending. Additional demineralized dentin discs (1 mm) were incubated in DMSO (1, 10, 50 and 100%) for 10, 30 and 60 min and the optical clearing effect was observed. The data were analyzed using ANOVA and Tukey's test (α=0.05) using SigmaPlot (Systat Software Inc., San Jose, CA). Compared to controls, HEMA uptake was significantly higher with all DMSO concentrations, and with 0.1% or higher ethanol concentrations (p < 0.05). HEMA uptake in DMSO-incubated specimens (0.01, 5 and 10%) was significantly higher than with the ethanol incubation. Significant increase in elastic moduli was observed with 50-100% DMSO-and only with 100% ethanol after 10 min incubation. The optical clearing effect of 50-100% DMSO-incubated dentin disks was observed starting from 10 min. The pretreatment of dentin surfaces with low concentrations of DMSO resulted in significant improvement of the penetration of monomers to demineralized dentin matrices. Increase in penetration of monomers combined with a reversible stiffening of dentin collagenous matrix may explain the previously shown increase in durability of wet-or dry-bonded adhesive interfaces with DMSO treatment.

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Influence of dimethyl sulfoxide used as a solvent on the physical properties and long-term dentin bonding of hydrophilic resins

Abstract: The use of DMSO as a new solvent in adhesive dentistry improves dentin bonding of relatively hydrophilic resins over time. 2% DMSO incorporation in BisGMA/HEMA resins should be sufficient to reduce bond strength loss without compromising polymer mechanical strength and physical properties.

Cited by 25 publications

References 39 publications

Dentin bonding systems: From dentin collagen structure to bond preservation and clinical applications

Dentin bonding systems: From dentin collagen structure to bond preservation and clinical applications

ZnCl₂ Incorporated into Experimental Adhesives: Selected Physicochemical Properties and Resin-Dentin Bonding Stability

Influence of polar solvents on permeability, stiffness and collagen dissociation of demineralized dentin

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Influence of dimethyl sulfoxide used as a solvent on the physical properties and long-term dentin bonding of hydrophilic resins

Cited by 25 publications

References 39 publications

Dentin bonding systems: From dentin collagen structure to bond preservation and clinical applications

Dentin bonding systems: From dentin collagen structure to bond preservation and clinical applications

ZnCl2 Incorporated into Experimental Adhesives: Selected Physicochemical Properties and Resin-Dentin Bonding Stability

Influence of polar solvents on permeability, stiffness and collagen dissociation of demineralized dentin

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Product

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ZnCl₂ Incorporated into Experimental Adhesives: Selected Physicochemical Properties and Resin-Dentin Bonding Stability