“…A number of pharmacologic therapies have been advocated, with mixed results [12,13]. Parenteral nutrition factors, specifically amino acid composition and lipid formulation, have also demonstrated mixed results [7,[14][15][16][17][18]. Case reports have suggested that the use of ω-3 fatty acid-based lipid formulations may improve hyperbilirubinemia, but studies performed in animal models suggest that this may be associated with increased hepatic fibrosis, despite normal biochemical markers [15,16].…”