Influence of diabetes mellitus on the invasive assessment of myocardial ischemia in patients with coronary artery disease

Abstract

High correlation and consistency are noted between the results of these methods. 4,6-8 However, discordant results between FFR and iFR/RFR might be observed in about 20% of cases. 4,9 -16 Thus, numerous efforts have been made to establish the mechanisms of and identify factors that lead to such a discrepancy. 4,17 Several clinical, angiographic, and hemodynamic predictors of differences between FFR and iFR/RFR, INTROduCTION Physiological assessment of coronary artery disease using fractional flow reserve (FFR), instantaneous wave -free ratio (iFR), and resting full -cycle ratio (RFR) has become the standard method for evaluating the functional significance of coronary artery lesions. 1-4 Notably, its use is recommended for revascularization decision -making in intermediate -grade stenoses of 50% to 90% on angiography. 1,3,5