Influence of detomidine on atrial fibrillation cycle length measured by intracardiac electrogram recording and by colour tissue <scp>D</scp>oppler imaging in horses

Decloedt, Annelies; Clercq, Dominique De; Vekens, Nicky Van Der; Verheyen, Tinne; Ven, S.; Loon, Gunther van

doi:10.1111/evj.12366

Cited by 10 publications

(11 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The AFCL measured in the left atrial free wall from the right parasternal 4‐chamber view was shorter compared to the other views, as has been described previously . The AFCL from this view did not show a significant increase after sotalol administration.…”

Section: Discussionsupporting

confidence: 78%

“…26 The AFCL measured in the left atrial free wall from the right parasternal 4-chamber view was shorter compared to the other views, as has been described previously. 17,18 The AFCL from this view did not show a significant increase after sotalol administration. In the 4 chamber view, the atrial myocardium is located at a large image depth and more artifacts are present.…”

Section: Discussionmentioning

confidence: 59%

“…The atrial fibrillatory rate was assessed from tissue Doppler velocity curves of the atrial myocardial walls, as described previously . In brief, tissue Doppler images were acquired from the left atrial free wall in a right parasternal 4‐chamber view, from the right atrial dorsal wall at the level of the tuberculum intervenosum in a right parasternal view and from the left atrial free wall in a left parasternal long axis view.…”

Section: Methodsmentioning

confidence: 99%

“…Tissue Doppler velocity curves were acquired off‐line by positioning a 5 × 5 mm sample volume in the atrial myocardial wall (Echopac software version 11.2, GE Healthcare, Diegem, Belgium). The atrial fibrillation cycle length (AFCL) was measured from consecutive loops with at least moderate quality, until a minimum of 30 AFCL were measured from each view (Figure ) . These 30 measurements then were averaged to obtain AFCL from each view.…”

Section: Methodsmentioning

confidence: 99%

“…The atrial fibrillatory rate was assessed from tissue Doppler velocity curves of the atrial myocardial walls, as described previously. 17,18 In brief, tissue Doppler images were acquired from the left atrial free wall…”

Section: Measurementsmentioning

confidence: 99%

See 4 more Smart Citations

Effect of sotalol on heart rate, QT interval, and atrial fibrillation cycle length in horses with atrial fibrillation

Decloedt

Broux

Clercq

et al. 2018

Veterinary Internal Medicne

View full text Add to dashboard Cite

BackgroundBased on its pharmacokinetic profile and electrophysiological effects in healthy horses, sotalol potentially could be used as a long‐term PO antiarrhythmic drug in horses.ObjectivesTo evaluate the effect of sotalol on heart rate (HR), QT interval, atrial fibrillatory rate, and success of cardioversion in horses with naturally occurring chronic atrial fibrillation (AF).AnimalsTwenty‐eight horses referred for transvenous electrical cardioversion of AF were treated with 2 mg/kg sotalol PO q12h for 3 days before cardioversion, and 13 horses underwent the same protocol without sotalol administration.MethodsRetrospective study. Before and after sotalol or no treatment, the HR was measured at rest and during an exercise test. The QT interval and atrial fibrillation cycle length (AFCL) were measured at rest using tissue Doppler velocity imaging.ResultsIn the control group, no significant differences were found between the 2 examinations. In the sotalol group, the HR at rest and during exercise was significantly lower after sotalol treatment, whereas the QT interval and AFCL measured by tissue Doppler increased significantly. Cardioversion to sinus rhythm was achieved in 25/28 horses in the sotalol group and all horses in the control group, but the median number of shocks and energy at cardioversion were significantly lower in the sotalol group.Conclusions and Clinical ImportanceIn horses with AF, sotalol administration results in class III antiarrhythmic effects and β‐blocking activity, with moderate HR reduction during exercise.

show abstract

Section: Discussionsupporting

confidence: 78%

Section: Discussionmentioning

confidence: 59%

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Measurementsmentioning

confidence: 99%

See 3 more Smart Citations

Effect of sotalol on heart rate, QT interval, and atrial fibrillation cycle length in horses with atrial fibrillation

Decloedt

Broux

Clercq

et al. 2018

Veterinary Internal Medicne

View full text Add to dashboard Cite

show abstract

Anaesthetic management for cardiac 3D electro‐anatomical mapping and radiofrequency catheter ablation in a horse with sustained atrial tachycardia

Phillips

Schauvliege

Decloedt

et al. 2022

Vet Record Case Reports

View full text Add to dashboard Cite

Atrial arrhythmias in horses are common, and novel catheter-based treatment techniques require the horse to be under general anaesthesia. A 3-year-old gelding, weighing 517 kilograms, presented for cardiac three-dimensional electro-anatomical mapping and radiofrequency ablation for treatment of sustained atrial tachycardia. The current case report describes a suitable anaesthetic protocol that included medetomidine and methadone as premedication, a combination of ketamine and diazepam for coinduction of anaesthesia and maintenance with isoflurane vaporised in an oxygen/air mixture with constant-rate infusions of medetomidine and lidocaine. Total anaesthesia time was 205 minutes. The current protocol did not negatively impact on the procedure performed, provided good haemodynamic stability for several hours and enabled a smooth good-quality recovery. The horse developed a triceps myopathy postoperatively, which was successfully treated and the horse was discharged 18 days following treatment.

show abstract

Disorders of the Cardiovascular System

Schwarzwald¹

2018

Equine Internal Medicine

View full text Add to dashboard Cite

Influence of detomidine on atrial fibrillation cycle length measured by intracardiac electrogram recording and by colour tissue Doppler imaging in horses

Abstract: Sedation facilitates noninvasive AFCL measurements but causes a slight increase in AFCL. Noninvasive AFCL measurements can be used as an indicator of atrial electrical remodelling, to study AF pathophysiology and to investigate the effect of anti-arrhythmic drugs.

Cited by 10 publications

References 31 publications

Effect of sotalol on heart rate, QT interval, and atrial fibrillation cycle length in horses with atrial fibrillation

Effect of sotalol on heart rate, QT interval, and atrial fibrillation cycle length in horses with atrial fibrillation

Anaesthetic management for cardiac 3D electro‐anatomical mapping and radiofrequency catheter ablation in a horse with sustained atrial tachycardia

Disorders of the Cardiovascular System

Contact Info

Product

Resources

About