Influence of custom foot orthoses on venous status: A quasi-experimental study

López‐López, Daniel; Araujo, Romeu; Losa‐Iglesias, Marta Elena; Becerro-de-Bengoa-Vallejo, Ricardo; Santos, António; Rodríguez‐Sanz, David; Calvo‐Lobo, César

doi:10.1016/j.jmbbm.2017.12.035

Cited by 9 publications

(17 citation statements)

References 18 publications

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“…Cause–effect studies and deep understanding of the mechanisms are needed to target leptin to modify the venous status. [45] Our study also suggests that inhibition of the prothrombotic effects of leptin may represent a novel therapeutic strategy for reducing DVT after TKA.…”

Section: Discussionmentioning

confidence: 71%

High preoperative serum leptin level is an independent risk factor for deep vein thrombosis after total knee arthroplasty in osteoarthritis patients

Zhou

Xue

et al. 2018

Medicine

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It suggests that a high leptin level may increase the risk of venous thromboembolism (VTE) in animal studies. However, clinical studies in this field are still largely unexplored. Our objective was to evaluate the relationship between the preoperative serum leptin levels and postoperative VTE incidence in osteoarthritis (OA) patients who underwent total knee arthroplasty (TKA) at our institute.We conducted a prospective and cross-sectional study in these OA patients from March 2014 to March 2016. Preoperative leptin levels were analyzed by Luminex assays. VTE was assessed preoperatively and on postoperative day 5 and 7. The potential risk factors for VTE were also documented.We enrolled 203 OA patients. No PE was detected and DVT was diagnosed in 34 patients postoperatively. There were significant differences between the median leptin levels in DVT group and non-DVT group [25.13 ng/mL (interquartile range, 14.51-44.31) vs 18.71 ng/mL (8.26-28.99), P = .007]. The relative risk of DVT significantly increased with natural logarithm (ln) leptin (per SD increase) (OR 2.37, 95% confidence interval (95% CI), 1.29-4.33, P = .005). Multivariate analyses adjusted for potential confounders showed ln leptin (per SD increase) was significantly associated with the relative risk of DVT (OR 2.17, 95% CI, 1.01-4.64, P = .046). When patients were subdivided into tertiles according to their leptin values, the OR for DVT increased with increasing tertiles of serum leptin (OR 1.03, 95% CI, 1.01-1.06, P for trend = .023).In the present study, our results indicate that a high preoperative leptin level may be an independent risk factor for postoperative DVT.

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Section: Discussionmentioning

confidence: 71%

High preoperative serum leptin level is an independent risk factor for deep vein thrombosis after total knee arthroplasty in osteoarthritis patients

Zhou

Xue

et al. 2018

Medicine

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“…Another study analyzed the effect of ankle joint immobilization with different shoes (i.e., cast, pneumatic walking boot) or positions of immobilization (i.e., neutral, equinus) [51]. Only one study collected data on insoles (i.e., customized foot orthotics) vs without insoles [22]. Five studies used consistent treadmill exercise (walking or running) [23,25,47,49,50], one used running exercise [46], five used an upright standing exercise (e.g., simulated work) [22,24,37,44,45], two used tip-toe movements [47,48] and one asked participants to simulate gait [51].…”

Section: Resultsmentioning

confidence: 99%

“…For all other items, "yes" was scored 1 and "no" and "unable to determine" were scored 0. Based on the risk of bias assessment scores, studies were classified as very high quality/very low risk of bias (26)(27)(28), good quality/low risk of bias (20)(21)(22)(23)(24)(25), fair quality/fair risk of bias (15)(16)(17)(18)(19) or poor quality/high risk of bias (� 14) [43]. Higher scores indicated less risk of bias than lower scores.…”

Section: Risk Of Bias and Quality Appraisalmentioning

confidence: 99%

“…Saggini et al [9] showed an improvement in the venous emptying capacity of the foot-calf veno-muscular system (in cavus foot) with shoes equipped with a specific type of foot orthotic (i.e., visco-elastic insoles). More recently, Lopéz-Lopéz et al [22] demonstrated an increase in venous return in the feet with shoes equipped with orthotics (i.e., customized with ethylene-vinyl acetate material). However, in addition to these technologies (i.e., foot compression devices, insoles and orthotics) to improve venous function, there are now shoe products (e.g., sandals, heelless shoes) that can improve venous flow [23][24][25] and might optimize recovery [26].…”

Section: Introductionmentioning

confidence: 99%

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The effects of shoe type on lower limb venous status during gait or exercise: A systematic review

et al. 2020

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This systematic review evaluated the literature pertaining to the effect of shoes on lower limb venous status in asymptomatic populations during gait or exercise. The review was conducted in accordance with PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. The PubMed-NCBI, EBSCO Host, Cochrane Library and Science Direct databases were searched (March 2019) for words around two concepts: shoes and venous parameters. The inclusion criteria were as follows: (1) the manuscript had to be published in an English-language peer-reviewed journal and the study had to be observational or experimental and (2) the study had to suggest the analysis of many types of shoes or orthotics on venous parameters before, during and/or after exercise. Out of 366 articles, 60 duplications were identified, 306 articles were analyzed, and 13 articles met the eligibility criteria after screening and were included. This review including approximately 211 participants. The methodological rigor of these studies was evaluated with the modified Downs and Black quality index. Nine studies investigated the effect of shoes on blood flow parameters, two on venous pressure and two on lower limb circumferences with exercise. Evidence was found that unstable shoes or shoes with similar technology, sandals, athletic or soft shoes, and customized foot orthotics elicited more improvement in venous variables than high-heeled shoes, firm shoes, ankle joint immobilization and barefoot condition. These venous changes are probably related to the efficiency of muscle pumps in the lower limbs, which in turn seem to be dependent on shoe features associated with changes in the kinetics, kinematics and muscle activity variables in lower limbs during gait and exercise.

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“…Biomechanically, the maximum ankle dorsiflexion during the stance phase of a normal gait occurs before heel lift, with the knee completely extended [ 1 ]. In the reviewed literature, static evaluation of ankle dorsiflexion range of movement shows that the minimum dorsiflexion movement for the ankle for normal gait is 10° of motion [ 3 , 21 , 22 , 23 , 24 ].…”

Section: Discussionmentioning

confidence: 99%

Effects of Compressive Stockings and Standard Stockings in Skin Temperature and Pressure Pain Threshold in Runners with Functional Ankle Equinus Condition

Rodríguez‐Sanz

Becerro-de-Bengoa-Vallejo

Iglesias

et al. 2018

JCM

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Objective: To assess clinical differences in the Achilles tendons of runners with ankle equinus wearing either compressive or standard stockings. Design: Case–control study. Methods: In this study, we conducted clinical examinations of 98 sportsmen (runners) with equinus, before and after 30 min of running on a treadmill; 49 runners wore compressive stockings and 49 wore standard stockings. Clinical assessments of the runners’ Achilles tendons were based on the pressure pain threshold (PPT) and skin temperature analysis. Results: Achilles tendon evaluations identified significant differences in skin temperature modification and PPT between the compressive and standard stocking groups. Conclusions: Based on our findings, we propose that higher skin temperatures are associated with lower pressure pain thresholds in the Achilles tendons of runners with ankle equinus.

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Influence of custom foot orthoses on venous status: A quasi-experimental study

Cited by 9 publications

References 18 publications

High preoperative serum leptin level is an independent risk factor for deep vein thrombosis after total knee arthroplasty in osteoarthritis patients

High preoperative serum leptin level is an independent risk factor for deep vein thrombosis after total knee arthroplasty in osteoarthritis patients

The effects of shoe type on lower limb venous status during gait or exercise: A systematic review

Effects of Compressive Stockings and Standard Stockings in Skin Temperature and Pressure Pain Threshold in Runners with Functional Ankle Equinus Condition

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