Influence of components of anesthesia on dynamics of stress markers in gynecological laparoscopic surgery.

Khalimonchyk, V.V.; Кlygunenko, O.М.

doi:10.26641/2307-0404.2019.3.181876

Cited by 3 publications

(3 citation statements)

References 13 publications

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“…With the continuous development of clinical minimally invasive and endoscopic techniques, laparoscopic surgery has been widely used in the gynecological field due to its advantages of fewer traumas, less pain, and faster recovery from surgery [ 1 ]. The advantages of propofol and fentanyl, such as the rapid onset of anesthesia and no accumulation of anesthetic effect, make them widely used in gynecological laparoscopic surgeries [ 2 , 3 ]. The fast development of laparoscopic surgery also leads to higher requirements for nursing staff in clinical practice, so as to improve the quality of nursing services and promote a more harmonious relationship between doctors and patients, which is beneficial to postsurgical recovery to a certain extent [ 4 , 5 ].…”

Section: Introductionmentioning

confidence: 99%

Targeted Perioperative Nursing Combined with Propofol and Fentanyl for Gynecological Laparoscopic Surgery

Yun

Chen

Zheng

2022

Evidence-Based Complementary and Alternative Medicine

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Objective. The aim of this study is to investigate the clinical effects of targeted perioperative nursing combined with propofol and fentanyl in gynecological laparoscopic surgery. Methods. Patients who were admitted to our hospital for gynecological laparoscopic surgeries from October 1, 2019 to November 30, 2021 were included in this retrospective study. Patients in group A received routine propofol and fentanyl. Patients in group B received targeted perioperative nursing on the basis of interventions in group A. The anesthetic effects, clinical indicators, mental health status, and adverse reactions were compared between the two groups. Results. A total of 84 qualified patients were retrieved. The total effective anesthesia rate, extubation time, operation time, consciousness recovery time, intraoperative blood loss, hospital stay, SAS score, SDS score, health status indicators, and adverse events in group B were all significantly better than those in group A ( P < 0.05 for all comparisons). Conclusion. Combined intervention (propofol + fentanyl + targeted perioperative care) for gynecological laparoscopic surgery patients has a significant anesthesia effect, which can effectively improve the patient's clinical indicators and mental health status and can also reduce the occurrence of adverse events. It has good safety and can be widely used in clinical practice.

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Section: Introductionmentioning

confidence: 99%

Targeted Perioperative Nursing Combined with Propofol and Fentanyl for Gynecological Laparoscopic Surgery

Yun

Chen

Zheng

2022

Evidence-Based Complementary and Alternative Medicine

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“…For patients undergoing laparoscopic radical resection of cervical cancer, the pain mainly stems from the abdominal incision and mostly intensifies after analgesic recovery. By blocking the anterior abdominal wall nerve, TAPB reduces the pain in the abdominal wall area, thereby achieving a promising and targeted analgesic effect (18)(19)(20)(21).…”

Section: Discussionmentioning

confidence: 99%

Efficacy of Transversus Abdominis Plane Block in Patients After Laparoscopic Radical Cervical Cancer Surgery

Gao

Wang

et al. 2022

Front. Surg.

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ObjectiveThis study aimed to evaluate the efficacy of transversus abdominis plane block (TAPB) in patients after laparoscopic radical cervical cancer surgery.MethodsA total of 120 patients with cervical cancer who underwent laparoscopic radical resection in the hospital from January 2019 to January 2020 were selected and concurrently assigned to either patient-controlled intravenous analgesia (PCIA) (Control group) or PCIA plus TAPB (Observation group) according to different methods. The visual analogscale (VAS), Bruggemann comfort scale (BCS), immune function indicators, hemodynamics, analgesia indicators, and postoperative recovery time were recorded and compared.ResultsThe Observation group had a lower VAS score and a higher BCS postoperatively compared with the Control group, and the difference was statistically significant. After the operation, immune function indexes of patients in the two groups were declined, and the difference was statistically significant. At 76 h after operation, the immune function indexes of the Control group were lower than the Observation group, and the difference was statistically significant. After the operation, the Control group obtained a higher mean arterial pressure (MAP) at extubation, and the difference was statistically significant. The Observation group outperformed the Control group in terms of analgesia indicators and postoperative recovery time, and the difference was statistically significant.ConclusionTAPB can enhance the analgesic effect of patients after laparoscopic radical resection of cervical cancer, stabilize their physical signs, has little effect on the patient's immune function, with a high safety profile.

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“…This multilevel response to stress depends on a number of endogenous and exogenous factors, namely age, sex, previous health, type and invasiveness of surgery, type of anesthesia, pain intensity, etc. [20]. The pathogenic nature of the surgical stress response has been proven, which significantly worsens the postoperative period and prolongs the rehabilitation time of patients.…”

Section: Discussionmentioning

confidence: 99%

Influence of Different Types of Anesthesia for Laparoscopic Hysterectomy on the Dynamics of Stress Hormones

Ткаченко

Zaychenko

2021

Eureka: HS

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The aim of the study – to evaluate the influence of different variants of anesthesia, including low-opioid (LOA) and opioid-free anesthesia (OFA), on the dynamics of the stress response during laparoscopic hysterectomy. Materials and methods: 102 patients were randomly allocated into 3 groups: 37 women assigned to receive a standard opioid-based anesthesia (OBA group), 33 women – LOA group and 32 patients OFA group. Results: The patients of OFA group after induction and intubation of the trachea showed a significant (p<0.05) increase in cortisol level by 155.4 % and 160.9 % compared with the OBA group and LOA group. After completion of the hysterectomy, regardless of the variant of anesthesia, the level of cortisol exceeded the preoperative one (pOBA=0.116, pLOA=0.049, pOFA=0.043). Two hours after surgery with standard anesthesia (OBA group) there was a further increase in the concentration of cortisol in the blood, exceeding the initial values by 142.9 % (p=0.043). Patients in the LOA group and OFA group tended to decrease cortisolemia. The changes in adrenaline & glucose levels were somewhat similar. Conclusion: Use of OFA is accompanied by an aggravation of the stress response at the stage of hysterectomy, which is manifested by an increase in the level of adrenaline and cortisol. The most adequate perioperative protection is inherent in low-opioid anesthesia, which is accompanied by a lower release of stress hormones during hysterectomy and in the postoperative period. Opioid-based anesthesia provides adequate intraoperative protection, but is accompanied by insufficient postoperative analgesia.

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Influence of components of anesthesia on dynamics of stress markers in gynecological laparoscopic surgery.

Cited by 3 publications

References 13 publications

Targeted Perioperative Nursing Combined with Propofol and Fentanyl for Gynecological Laparoscopic Surgery

Targeted Perioperative Nursing Combined with Propofol and Fentanyl for Gynecological Laparoscopic Surgery

Efficacy of Transversus Abdominis Plane Block in Patients After Laparoscopic Radical Cervical Cancer Surgery

Influence of Different Types of Anesthesia for Laparoscopic Hysterectomy on the Dynamics of Stress Hormones

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