Influence of Chlorella powder intake during swimming stress in mice

Chlorella-derived multicomponent supplementation increases aerobic endurance capacity in young individuals

“…The previous study, which found 13,683 genes expression after forced swimming in mice, reported that 774 genes were downregulated and 220 genes were upregulated in Chlorella intake mice, whereas the 774 genes were upregulated and the 220 genes were downregulated in normal diet mice. ( 5 ) Immune response- and oxidoreductase activity-associated genes were included in the downregulated genes with Chlorella supplementation and angiogenesis-related genes were included in the upregulated genes. Although it is currently unknown which genes were implicated in an increase in maximal swimming time in mice on a diet including Chlorella powder, these genes may provide keys to elucidate the mechanisms underlying an improvement of aerobic endurance capacity with Chlorella supplementation.…”

“…Since mice in the control group were fed a standard diet, it is reasonable to hypothesize that there were no malnourished mice in the previous study investigating effects of Chlorella supplementation on maximal swimming time. ( 5 ) However, it is possible that subjects with malnutrition were included in our human study. Many studies have reported that skipping breakfast, eating fast food, and dieting to lose weight may lead to malnutrition in young adults.…”

“…For example, a previous animal study reported that maximal swimming time in mice increased after 14 days on a diet including Chlorella powder compared to no change in swimming performance on a normal (i.e., presumably non-deficient) diet. ( 5 ) Chlorella is a unicellular green alga that grows in fresh water and contains a variety of nutrients including amino acids (e.g., branched-chain amino acids [BCAAs] and arginine), carbohydrates, vitamins, and minerals. ( 6 , 7 ) BCAAs and arginine can potentially increase aerobic endurance performance in individuals without overt nutritional deficiencies.…”

Metabolic and motor activity effects of microalgae (Chlorella vulgaris) in laboratory mice

“…Полученные нами данные о более эффективном восстановлении активности животных, употреблявших хлореллу, в ответ на стресси-рующее воздействие согласуются с результатами, выяв-ленными при изучении эффектов хлореллы в терапии БДР (Panahi et al, 2015), и свидетельствуют о потенцирующем влиянии хлореллы на активность животных. Аналогичные результаты получены при исследовании стрессирующих эффектов принудительного плавания на выносливость мышей (Mizoguchi et al, 2011). Показано, что самцы мы шей линии BALB/c, употреблявшие хлореллу в концентра-ции 0.5 %, обладали большей выносливостью и плавали дольше, чем животные из контрольной группы.…”

Microalgae of the Chlorophyceae Class: Potential Nutraceuticals Reducing Oxidative Stress Intensity and Cellular Damage

“…Also, it stimulates the production of metallothionein in the small intestine. Isolation of phophorylated polysaccharides from algae: the inmmunostimulatory principle of Chlorella pyrenoidosa (Suarez et al, 2010) The Chlorella polysaccharides increases the production of NO in macrophages enhancing the innate immune response, mediated by Toll-like receptors (TLR-4) Influence of Chlorella powder intake during swimming stress in mice (Mizoguchi et al, 2011) Chlorella vulgaris exhibits an antioxidant activity, reducing the lipoperoxidation, avoiding the DNA damage. However it does not show hypoglycemic activity Table 3.…”