Influence of buffer solution on structure and electrochemical properties of poly(3,4-ethylenedioxythiophene)/poly(styrenesulfonate) hydrogels

Słoniewska, Anna; Kasztelan, Mateusz; Berbeć, Sylwia; Pałys, Barbara

doi:10.1016/j.synthmet.2020.116363

Cited by 10 publications

(5 citation statements)

References 56 publications

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“…Subsequently, the result from Figure 4A shows the improved electrochemical behavior can be attributed to the excellent electrical conductivity of the Ti 3 C 2 and GQD present on the electrode surface could accelerate the electron transfer rate at the electrode/electrolyte interface [43][44][45]. In regard to the presence of Ti 3 C 2 and GQD, they provide additional active surface area, thus resulting in better exposure of electroactive sites compared to PEDOT:PSS alone [23,46].…”

Section: Discussionmentioning

confidence: 97%

Label Free Glucose Electrochemical Biosensor Based on Poly(3,4-ethylenedioxy thiophene):Polystyrene Sulfonate/Titanium Carbide/Graphene Quantum Dots

et al. 2021

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The electrochemical biosensor devices based on enzymes for monitoring biochemical substances are still considered attractive. We investigated the immobilization of glucose oxidase (GOx) on a new composite nanomaterial poly(3,4-ethylenedioxythiophene): polystyrene sulfonate (PEDOT:PSS)/titanium carbide,(Ti3C2)/graphene quantum dots(GQD) modified screen-printed carbon electrode (SPCE) for glucose sensing. The characterization and electrochemical behavior of PEDOT:PSS/Ti3C2/GQD towards the electrocatalytic oxidation of GOx was analyzed by FTIR, XPS, SEM, cyclic voltammetry (CV), and differential pulse voltammetry (DPV). This composite nanomaterial was found to tend to increase the electrochemical behavior and led to a higher peak current of 100.17 µA compared to 82.01 µA and 95.04 µA for PEDOT:PSS and PEDOT:PSS/Ti3C2 alone. Moreover, the detection results demonstrated that the fabricated biosensor had a linear voltammetry response in the glucose concentration range 0–500µM with a relatively sensitivity of 21.64 µAmM−1cm−2 and a detection limit of 65 µM (S/N = 3), with good stability and selectivity. This finding could be useful as applicable guidance for the modification screen printed carbon (SPCE) electrodes focused on composite PEDOT:PSS/Ti3C2/GQD for efficient detection using an enzyme-based biosensor.

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Section: Discussionmentioning

confidence: 97%

Label Free Glucose Electrochemical Biosensor Based on Poly(3,4-ethylenedioxy thiophene):Polystyrene Sulfonate/Titanium Carbide/Graphene Quantum Dots

et al. 2021

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“…In all sample cases, after 24 h, silicone fragments from the matrix appeared in the medium; this was more pronounced for the blank reference sample (Figure 6a) and the vitamin B1 liner (Figure 6c). This process was continuous for the reference sample over the full 72 h, while for the samples containing vitamins, these fragments occurred only in the first 24 h. For the vitamin A liner, the main products consisting of vitamin A appeared after 72 h, while for the vitamin B1 liner and the vitamin B6 liner, the vitamin fragments appeared after 48 h. This behavior can be explained by the influence of the phosphate buffer on the silicone matrix and the diffusion of the vitamin fragments in the medium [29]. However, the release of the vitamins is beneficial in this case, as these vitamins have therapeutic effects on the oral mucosa [30].…”

Section: Hydrolytic Stabilitymentioning

confidence: 95%

The Impact of the Addition of Vitamins on a Silicone Lining Material to the Oral Mucosa Tissue—Evaluation of the Biocompatibility, Hydrolytic Stability and Histopathological Effect

Gradinaru,

Ciubotaru,

Butnaru

et al. 2023

Medicina

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Background and Objectives: One’s quality of life depends on overall health, and in particular, oral health, which has been and continues to become a public health issue through frequent manifestations in various forms, from simple oral stomatitis (inflammations of the oral cavity) to the complicated oral health pathologies requiring medical interventions and treatments (caries, pulp necrosis and periodontitis). The aim of this study focused on the preparation and evaluation of vitamins (vitamin A, B1 and B6) incorporated into several silicone-based lining materials as a new alternative to therapeutically loaded materials designed as oral cavity lining materials in prosthodontics. Materials and Methods: Silicone-based liners containing vitamins were prepared by mixing them in solution and becoming crosslinked, and then they were characterized using Fourier-transform infrared (FT-IR) spectroscopy to confirm the incorporation of the vitamins into the silicone network; scanning electron microscopy (SEM) to evidence the morphology of the liner materials; dynamic vapor sorption (DVS) to evaluate their internal hydrophobicity, swelling in environments similar to biological fluids and mechanical test to demonstrate tensile strength; MTT to confirm their biocompatibility on normal cell cultures (fibroblast) and mucoadhesivity; and histopathological tests on porcine oral mucosa to highlight their potential utility as soft lining materials with improved efficiency. Results: FT-IR analysis confirmed the structural peculiarities of the prepared lining materials and the successful incorporation of vitamins into the silicone matrix. The surface roughness of the materials was lower than 0.2 μm, while in cross-section, the lining materials showed a compact morphology. It was found that the presence of vitamins induced a decrease in the main mechanical parameters (strength and elongation at break, Young’s modulus) and hydrophobicity, which varied from one vitamin to another. A swelling degree higher than 8% was found in PBS 6.8 (artificial saliva) and water. Hydrolytic stability studies in an artificial saliva medium showed the release of low concentrations of silicone and vitamin fragments in the first 24 h, which increased the swelling behavior of the materials, diffusion and solubility of the vitamins. The microscopic images of fibroblast cells incubated with vitamin liners revealed very good biocompatibility. Also, the silicone liners incorporating the vitamins showed good mucoadhesive properties. The appearance of some pathological disorders with autolysis processes was more pronounced in the case of vitamin A liners. Conclusions: The addition of the vitamins was shown to have a beneficial effect that was mainly manifested as increased biocompatibility, hydrolytic stability and mucoadhesiveness with the mucosa of the oral cavity and less of an effect on the mechanical strength. The obtained lining materials showed good resistance in simulated biological media but caused a pronounced autolysis phenomenon, as revealed by histopathological examination, showing that these materials may have broad implications in the treatment of oral diseases.

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“…The process entails the alteration of the oxidation state of the iron ion within the heme group present in HRP, resulting in the discharge of electrons that are subsequently transmitted to the electrode, thereby inducing a current peak [176,177]. Conductive PEDOT: PSS plays a key role in the direct electron transfer between the enzyme and the electrode [178]. In the chemiresistive mode, the sensing mechanism relies on the conformational change of PEDOT between two molecular structures, quinoid and benzoid, in response to H 2 O 2 .…”

Section: Conductive Polymersmentioning

confidence: 99%

“…The conformational change to the coil-like benzoid structure reduces elec-tron mobility [126,179]. The HRP and H 2 O 2 reaction initiates the PEDOT conformational change to the quinoid structure, resulting in higher conductivity [178]. The amperometric sensor showed a rapid response time of less than 6 seconds, selectivity towards common interferents, and a broad detection range spanning from 100 µM to 101.6 mM.…”

Section: Conductive Polymersmentioning

confidence: 99%

Flexible sensors for food monitoring. Part I: Principle

Luo,

Nikitina,

Xiao

2024

Food systems

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Monitoring and maintaining food quality, safety, and authenticity are the most important concerns in the food industry. The cutting-edge flexible sensors for food monitoring precisely meet the needs of acquiring information on multiple parameters in small space and more reasonable layout, providing data on mechanical deformations, and conformably attaching to arbitrarily curved surfaces. Flexible sensing materials with a large specific surface area, high carrier mobility and carrier density, dense active sites, outstanding tunability, and processability, such as two-dimensional carbon nanomaterials, conductive polymers, and nanohybrid materials, have further improved the sensitivity, stability, and selectivity of flexible sensors. This article attempts to critically review state-of-the-art developments with respect to materials, fabrication techniques, and sensing mechanisms of devices, as well as the applications of the electrically-transduced flexible sensors. In addition, this review elaborates on the transduction mechanisms of several typical transducers, with a focus on the physics behind, including the modulation of doping level, Schottky barrier, and interfacial layer that typically lead to changes in conductivity, work function, and permittivity. We also highlight the benefits, technical challenges with corresponding solutions of current flexible sensors, and discuss potential strategies to overcome limitations in energy consumption, quantify the trade-offs in maintaining quality and marketability, optimize wireless communication, and explore new sensing patterns.

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Influence of buffer solution on structure and electrochemical properties of poly(3,4-ethylenedioxythiophene)/poly(styrenesulfonate) hydrogels

Cited by 10 publications

References 56 publications

Label Free Glucose Electrochemical Biosensor Based on Poly(3,4-ethylenedioxy thiophene):Polystyrene Sulfonate/Titanium Carbide/Graphene Quantum Dots

Label Free Glucose Electrochemical Biosensor Based on Poly(3,4-ethylenedioxy thiophene):Polystyrene Sulfonate/Titanium Carbide/Graphene Quantum Dots

The Impact of the Addition of Vitamins on a Silicone Lining Material to the Oral Mucosa Tissue—Evaluation of the Biocompatibility, Hydrolytic Stability and Histopathological Effect

Flexible sensors for food monitoring. Part I: Principle

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