Influence of bilirubin on the binding of 3,4-benzypyrene by blood proteins

Anghileri, L. J.

doi:10.1016/0304-4165(67)90084-0

Biochimica et Biophysica Acta (BBA) - General Subjects

1967

DOI: 10.1016/0304-4165(67)90084-0

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Influence of bilirubin on the binding of 3,4-benzypyrene by blood proteins

L. J. Anghileri

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1968

1979

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Incubation of 3,4-benzo(a)pyrene with serum fractions: Effect on tumor production

Stenbäck

Curtis

Rowland

et al. 1979

J. Cancer Res. Clin. Oncol.

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The effect on tumor formation in Swiss mice of incubation of 3,4-Benzo(a)pyrene [B(a)P]either with saline or saline containing serum, gamma-globulin or albumin (form mouse or rabbit) was investigated. A high incidence of sarcomas (80--100%) was obtained in Swiss mice by B(A)P incubated in vitro with rabbit serum, rabbit gamma-globulin, mouse serum, mouse gamma-globulin, and saline. A lower incidence (60--65%) was obtained with B(a)P incubated with mouse serum, mouse albumin, and rabbit albumin. The data suggest that binding of B(a)P to protein, particularly to albumin, significantly decreases the biological activity of B(a)P.

show abstract

Incubation of 3,4-benzo(a)pyrene with serum fractions: Effect on tumor production

Stenbäck

Curtis

Rowland

et al. 1979

J. Cancer Res. Clin. Oncol.

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show abstract

In vitro binding of 3,4-benzpyrene to albumin

Anghileri

1968

European Journal of Pharmacology

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Bilirubin Binding and Kernicterus

Diamond

1969

Advances in Pediatrics

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Influence of bilirubin on the binding of 3,4-benzypyrene by blood proteins

Cited by 3 publications

References 3 publications

Incubation of 3,4-benzo(a)pyrene with serum fractions: Effect on tumor production

Incubation of 3,4-benzo(a)pyrene with serum fractions: Effect on tumor production

In vitro binding of 3,4-benzpyrene to albumin

Bilirubin Binding and Kernicterus

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