Influence of BAS-145138 on the Activity of Sulfonylurea and Imidazolinone Herbicides

Abstract

This study demonstrates that corn can be partially safened by BAS-145138 against sulfonyl­urea and imidazolinone herbicides. The corn seeds were impregnated with BAS-145138 by soaking the seeds for 6 h in solutions of the safener. BAS-145138 had no effect on corn growth. However, corn shoot and root growth in length, fresh weight, and dry weight was partially protected by BAS-145138 from the phytotoxic effects of the sulfonylurea herbicides thiametu­ron and CGA -136872. Similar protection was given to corn against the phytotoxic activity of the imidazolinone herbicides imazapyr, imazaquin, and imazethapyr. This study suggests that corn could be safened with BAS-145138 against the phytotoxic effects of residual amounts of sulfonylurea and imidazolinone herbicides found in rotations take place.

Effect of BAS-145–138 on the phytotoxicity of imazaquin and metsulfuron-methyl

“…This concentration of safener produced significant protection from injury due to 400, 1200, and 4000 nM imazaquin. Similar results were obtained with 1 mM BAS-145-138 by Devlin and Zbiec (1991). BAS-145-138 provides a 1.5x safening effect (defined as the ratio of the Iso value for the safened versus unsafened seedlings).…”

“…The efficacy of BAS-145-138 as a safener for several imidazolinone and sulfonylurea herbicides has been partially evaluated. Corn shoot and root growth in length, fresh weight, and dry weight were partially protected by BAS-145-138 from the phytotoxic activity of the imidazolinone herbicide imazaquin (Devlin and Zbiec 1991). BAS-145-138 was also moderately effective in protecting corn from injury due to chlorimuron-ethyl (Lamoureux and Rusness 1991) but it reduced the herbicidal effect of three other sulfonylurea herbicides on corn (Devlin and Zbiec 1990).…”

“…The selectivity of both herbicides is due to a more rapid metabolism of the herbicide into non-toxic metabolites in tolerant than in susceptible species (Brown 1990;Shaner and Robson 1985). Although the mode of action of these herbicides is well documented, BAS-145-138 has only been tested as a potential safener against imazaquin in young plants (Devlin and Zbiec 1991) and has not been tested with metsulfuron-methyl.…”

Protective effect of two synthetic compounds against chlorsulfuron injury in maize ( Zea mays L.)

“…Table 2 Safening influence of 1-(4-fluorophenylthiocarbamoyl)-4-methylpiperazine (B-6) on the herbicidal effect of chlorsulfuron (CS) on the growth of maize depending on the time between the application of herbicide and the tested compound (Means ± SE, n=6) Studies on the mode of action of chlorsulfuron have shown that this herbicide appears to block the activity of acetolactate synthase (ALS, EC 4.1.3.18), leading to a decrease in the levels of three amino acids (valine, leucine and isoleucine). Consequently, the protein synthesis so necessary for plants is eventually terminated and the treated plant dies (Devlin and Zbiec, 1991). However, Clayton and Reynolds (1991) reported that protein synthesis is not inhibited by chlorsulfuron.…”

Synthesis, Crystal Structure and Biological Activity of Novel N‐substituted Diazabicyclo Derivatives

“…Dichloroacetyl diazabicyclo derivatives were reported as a novel kind of herbicide safener . They can protect crops from injury by chlorine acetamide herbicides, sulfonylurea herbicides, and imidazolinone herbicides .…”