For some applications of plastic materials, such as polystyrene, an important role is played by the wettability of the material. One of the methods of modifying material properties such as water contact angle is using nonthermal plasma. In this study, a radio-frequency atmospheric -pressure plasma jet source has been applied to the surface modification of a high-impact polystyrene film. The measurements show a dependence between the change in the water contact angle and the operating parameters of a nonequilibrium plasma treatment, such as the composition of the working gas, the flow rate, the distance from the plasma zone, and the discharge power.