Influence of aortic valve replacement, prosthesis type, and size on functional outcome and ventricular mass in patients with aortic stenosis

Abstract

Patients undergoing aortic valve replacement had an improvement in functional status, as well as systolic and diastolic left ventricular function, and a reduction in left ventricular mass index, irrespective of prosthesis size and type. Mechanical valves are somewhat less obstructive than stented bioprosthetic valves of the same size. They are also associated with a concomitantly more pronounced reduction of left ventricular mass.

Left ventricular mass: impact on left ventricular contractile function and its reversibility in patients undergoing aortic valve replacement

“…The influences of prosthetic valve type and size, and time following surgery on postoperative outcomes have been demonstrated in previous studies [9,[16][17][18][19][20][21]. In the present series of patients, only mechanical or stented biologic prostheses were implanted.…”

Impact of transcatheter aortic valve implantation on the left ventricular mass

“…LVMI is an index used in the evaluation of LVH. It is known that, LVMI decreases with the reduction of LV afterload after s-AVR and as a result, improvement in myocardial ischemia, functional capacity and long-term prognosis is observed [12,13]. The regression in LVMI after s-AVR is believed to be more important than valvular gradient as a prognostic factor [14][15][16].…”

Four year follow up of aortic valve replacement for isolated aortic stenosis: a link between reduction in pressure overload, regression of left ventricular hypertrophy, and diastolic function

“…Aortic valve replacement reduces pressure overload to a variable extent, depending on the type of artificial valve,6 14 29 and leads to regression of hypertrophy 930 Improvement of diastolic function after aortic valve replacement has been mainly attributed to the subsequent regression of left ventricular hypertrophy 9.…”