Influence of age and gender on thoracic vertebral body shape and disc degeneration: an MR investigation of 169 cases

Goh, S.; Tan, Celia Ia Choo; Price, Roger I.; Edmondston, Stephen J.; Song, Swithin; Davis, S.; Singer, Kevin

doi:10.1046/j.1469-7580.2000.19740647.x

Cited by 66 publications

(45 citation statements)

References 28 publications

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“…Miller et al (1988) studied 600 disc specimens from 237 cadavers, and reported that disc degeneration was detected in 16% of patients who died in their 20s, while disc degeneration was detected in 98% of patients who died in their 70s. At the time, men of all ages exhibited greater disc degeneration compared to women, and similar results have been reported from studies using magnetic resonance imaging (MRI) and surgery (Goh S et al, 2000;Vucetic et al, 1999). In addition, other studies have reported a correlation between obesity and disc degeneration (Like et al, 2005;Rodacki et al, 2005, Hangai et al, 2008.…”

Section: Age Sex and Body Weightsupporting

confidence: 71%

Effect of Workload on Musculoskeletal Degeneration

Kim¹,

Kim²,

Kang³

et al. 2014

Journal of the Ergonomics Society of Korea

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Objectiv e: The aim of this study is to investigate the effect of workload on musculoskeletal degeneration. Background:It is important that workers maintain a health body for a long time as a measure of aging workers. In order do so, it is necessary to find out if workload can effect on musculoskeletal degeneration.Method: Epidemiological studies on workload or occupation and disc degeneration, osteoarthritis of knee were identified through database and bibliography searches.Results: Epidemiological studies showed that workload certainly effect on musculoskeletal degeneration. But we couldn't know which of individual factors and occupational factors further contribute to the musculoskeletal degeneration. And we could find that studies on workload and genetic factors were very few. In addition, there was also very few studies that it was possible interaction between individual factors as obesity and occupational factors as heavy manual lifting.Conclusion: Our reviews suggest that it need to conduct study between workload and genetic factors for musculoskeletal degeneration. This further study can identify attributable risk of workload for musculoskeletal degeneration, and contribute to the measure of aging workers.Application: This paper can help to establish research plan for the measure of aging workers.

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Section: Age Sex and Body Weightsupporting

confidence: 71%

Effect of Workload on Musculoskeletal Degeneration

Kim¹,

Kim²,

Kang³

et al. 2014

Journal of the Ergonomics Society of Korea

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“…The target of the present investigation was to determine the role of age for this topic, although age should not be considered to be the sole factor for spinal degeneration [6]. So far frontal plane parameters have not been assumed to be depending on age [7,9,14,19,24]. In factor analyses, we found rotated component models that were comparable within the patients' subsamples, but different from the controls.…”

Section: Discussionmentioning

confidence: 79%

“…Parameters of the sagittal plane were extracted as being associated with low back pain, too. But with respect to the literature and inconsistency of different multivariate analysis approaches, those parameters also might to some extent be affected by aging and degeneration [7,9,14,19,24]. Despite assessment-specific limitations for the lumbosacral transition and despite a missing subsample of older controls, due to the inclusion criterion set prior to the investigation, we conclude that frontal plane trunk imbalance remains a low back pain indicator irrespective of age, while it was not possible to tell if it is the cause or a symptom of unspecific low back pain complaints.…”

Section: Discussionmentioning

confidence: 99%

“…Using video rasterstereography and multivariate analysis procedures, frontal plane (e.g., trunk imbalance and pelvis torsion) and sagittal plane (e.g., trunk inclination, lordosis angle) spine shape parameters could be identified to be associated with chronic low back pain in an adult population, ranging in age from 19 to 79 years [20][21][22]. In view of the corresponding literature, especially the sagittal plane parameters could have been affected by interfering influences of age [7,9,14,19,24]. The present investigation was aiming at separating age influences from low back pain-related spinal alignment deviations.…”

Section: Introductionmentioning

confidence: 99%

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Spinal alignment in low back pain patients and age-related side effects: a multivariate cross-sectional analysis of video rasterstereography back shape reconstruction data

2013

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Purpose Spinal form in the sagittal plane and asymmetries of spinal alignment in the frontal plane were identified earlier to be associated with low back pain. This study was aiming at investigating whether age was influencing the significance of these findings. Methods Spinal alignment of 155 older and 58 younger low back pain patients was investigated using non-invasive video rasterstereography and compared to 192 pain free controls. Trunk inclination and imbalance, pelvis tilt and torsion, and the thoracic kyphosis and lumbar lordosis angle served as dependent variables, which were analyzed using multivariate procedures. Results Frontal plane parameters-trunk imbalance (k [ 0.60) in combination with pelvis tilt (k [ 0.64)-constituted an independent component in a factor analysis model of spine shape parameters in younger and older patients, but not in pain free controls. Trunk imbalance (frontal), trunk inclination (sagittal) and partially thoracic kyphosis angle (sagittal) were extracted to separate patients from controls (discriminant coefficients [0.50). Age could not be excluded as interfering variable for the lumbar lordosis angle. Significant univariate analyses revealed higher effect sizes for trunk imbalance and inclination (g 2 [ 0.07) than for lordosis, kyphosis or pelvic parameters (g 2 \ 0.06). Conclusions In line with corresponding findings trunk imbalance remained a low back pain-associated parameter not depending on age. Over all, sagittal trunk inclination and the thoracic kyphosis angle could not be established as being completely free from age influences, while the lumbar lordosis angle played a minor role and seemed to be influenced more by age than by low back pain in this rasterstereography study.

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“…Several studies so far used MRI to investigate the relationship of disc height and disc degeneration. [10][11][12] Frobin et al 10 and Luoma et al 12 found that disc height decrease appears not to be associated with early degeneration. However, no quantitative data on the effect of disc degeneration on disc volume and shape is available.…”

Section: Introductionmentioning

confidence: 99%

Effect of aging and degeneration on disc volume and shape: A quantitative study in asymptomatic volunteers

Pfirrmann

Metzdorf

Elfering

et al. 2006

Journal Orthopaedic Research

126

105

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Debate continues on the effect of disc degeneration and aging on disc volume and shape. So far, no quantitative in vivo MRI data is available on the factors influencing disc volume and shape. The objective of this MRI study was to quantitatively investigate changes in disc height, volume, and shape as a result of aging and/or degeneration omitting pathologic (i.e., painful) disc alterations. Seventy asymptomatic volunteers (20-78 years) were investigated with sagittal T1-and T2-weighted MR-images encompassing the whole lumbar spine. Disc height was determined by the Dabbs method and the Farfan index. Disc volume was calculated by the Cavalieri method. For the disc shape the ''disc convexity index'' was calculated by the ratio of central disc height and mean anterior/posterior disc height. Disc height, disc volume, and the disc convexity index measurements were corrected for disc level and the individuals age, weight, height, and sex in a multilevel regression analysis. Multilevel regression analysis showed that disc volume was negatively influenced by disc degeneration ( p < 0.001) and positively correlated with body height ( p < 0.001) and age ( p < 0.01). Mean disc height and the disc convexity index were negatively influenced by disc degeneration but not by gender, weight, and height. Disc height was positively correlated with age ( p < 0.01). From the results of this study, it can be concluded that disc degeneration generally results in a decrease of disc height and volume as well as a less convex disc shape. In the absence of disc degeneration, however, age tends to result in an inverse relationship on disc height, volume, and shape. ß

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Influence of age and gender on thoracic vertebral body shape and disc degeneration: an MR investigation of 169 cases

Cited by 66 publications

References 28 publications

Effect of Workload on Musculoskeletal Degeneration

Effect of Workload on Musculoskeletal Degeneration

Spinal alignment in low back pain patients and age-related side effects: a multivariate cross-sectional analysis of video rasterstereography back shape reconstruction data

Effect of aging and degeneration on disc volume and shape: A quantitative study in asymptomatic volunteers

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