Influence of acute exercise of varying intensity and duration on postprandial oxidative stress

Abstract

In a sample of healthy, well-trained men, neither aerobic nor anaerobic exercise attenuates postprandial oxidative stress in response to a high-fat meal.

Effects of Postmeal Walking on Postprandial Glucose Control and Oxidative Stress

“…Therefore, the meal used in the present study should have been adequate to elicit an oxidative response. Furthermore, the subjects in the present study had IFG, lower plasma antioxidants, and higher resting oxidative stress levels than what is commonly found in healthy populations (Canale et al, 2014). Since individuals with impaired glucose regulation are more susceptible to increased levels of postprandial oxidative stress (Tucker et al, 2008), it is difficult to explain the lack of observable effect of our test meal on markers of oxidative stress in the present study.…”

“…Several catalase gene polymorphisms have been identified and shown to be associated with diabetes (Banerjee & Vats, 2014), and catalase deficiency (acatalasemia) is a leading cause of oxidative stress and macrovascular complications (Banerjee & Vats, 2014;Petrovič, 2014). A recent study by Canale, Farney, McCarthy, & Bloomer (2014) assessed the impact of acute exercise on postprandial oxidative stress and showed a significant reduction in antioxidant defenses, including catalase and superoxide dismutase, at 2 and 4 hours following a lipid-rich meal, although contrary to other studies (Michailidis et al, 2007), there was no difference in catalase between exercise conditions.…”

“…To date, the effect of acute exercise on postprandial oxidative stress has been assessed in four studies involving both healthy (Canale et al, 2014;Clegg et al, 2007;McClean et al, 2007) and prediabetic (Melton et al, 2009) individuals. All of the studies assessed the impact of a single aerobic exercise bout on markers of oxidative stress and/or antioxidant capacity following a high fat meal.…”

“…All of the studies assessed the impact of a single aerobic exercise bout on markers of oxidative stress and/or antioxidant capacity following a high fat meal. Of these, two found a significant change in oxidative markers during the exercise condition, compared with the control condition (Clegg et al, 2007;McClean et al, 2007), while two showed no effect (Canale et al, 2014;Melton et al, 2009). A series of studies by McClean and colleagues provided the first evidence that acute exercise could influence postprandial dymetabolism and markers of oxidative stress (Clegg et al, 2007;McClean et al, 2007).…”

“…The lack of observable effect of our test meal to induce oxidative stress during the control condition is unfortunate and makes it difficult to elucidate the potential impact of walking on attenuating the oxidative response. Many studies have indicated an increased oxidative response following ingestion of a mixed meal; however, the meal is often high in fat and designed to measure plasma triglyceride levels and subsequent oxidative stress (Canale et al, 2014;Clegg et al, 2007;McClean et al, 2007;Melton et al, 2009). Nevertheless, both hyperlipidemia and hyperglycemia in the postprandial period are known to induce oxidative stress (Gergersen et al, 2012), and high glycemic meals have resulted in a rise of oxidative products in healthy (Ceriello et al, 1999;Gregersen et al, 2012;Kasuya et al, 2015) and diabetic (Ceriello et al, 1998) subjects.…”