Infliximab in the treatment of hepatic vein thrombosis (Budd-Chiari syndrome) in three patients with Behcet's syndrome

Behçet's disease – a contemporary review

“…Thromboses of the superior and inferior vena cava (occur 0.2-9% of cases), of dural sinuses and of supra-hepatic veins (Budd-Chiari syndrome -in 2-3.2% of patients), and pulmonary arterial aneurysms (1%) can occur and are associated with a poor prognosis [73][74][75]141].…”

The Role of Biological Therapies in the Management of Systemic Vasculitis

“…Interestingly, pulmonary embolisms are very rare. Venous thrombosis can develop in other body locations, as suprahepatic veins -leading to Budd-Chiari syndrome (Seyahi et al, 2007) -or intracranial venous sinuses, as previously commented. Arterial involvement is lees frequent (<5%), but associated with poorer outcomes.…”

Vascular Manifestations of Behçet’s Disease

“…But only a limited number of studies about these agents have been published [91][92][93][94]. In contrast, several studies have raised caution regarding the possibility of development of thrombophlebitis as a side effect of infliximab in BD patients [95,96]. Further research is needed to clarify the efficacy and safety of anti-TNF-α agents in the treatment of vascular involvement in BD.…”