Inflammatory pseudotumor of the parapharyngeal space: A case report

Maruya, Shin-ichiro; Miura, Kouki; Tada, Yuichiro; Masubuchi, Tatsuo; Nakamura, Narihiro; Fushimi, Chihiro; Sakashita, Tetsuya; Monma, Tsutomu; Kamata, Shinkichi

doi:10.1016/j.anl.2009.08.002

Cited by 29 publications

(23 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In the head and neck region, IgG4-related IPTs of the salivary glands, lacrimal glands, and pituitary glands are well known; however, nasal/paranasal, 7 dura mater, 8 and parapharyngeal space 9 lesions have also been reported. Our report describes a case of IgG4-related IPT of the trigeminal nerve without involvement of any of the preferential organs.…”

Section: Discussionmentioning

confidence: 99%

IgG4-Related Inflammatory Pseudotumor of the Trigeminal Nerve: Another Component of IgG4-Related Sclerosing Disease?

Katsura¹,

Morita²,

Horiuchi³

et al. 2010

AJNR Am J Neuroradiol

View full text Add to dashboard Cite

IgG4-related IPTs have been reported in various sites and may form part of the spectrum of systemic IgG4-related sclerosing disease. Some pseudotumors are clinically and radiologically indistinguishable from malignant tumors. We present the first case of an IgG4-related IPT of the trigeminal nerve diagnosed histopathologically without involvement of any of the common sites. The trigeminal nerve pseudotumor may represent a component of IgG4-related sclerosing disease.

show abstract

Section: Discussionmentioning

confidence: 99%

IgG4-Related Inflammatory Pseudotumor of the Trigeminal Nerve: Another Component of IgG4-Related Sclerosing Disease?

Katsura¹,

Morita²,

Horiuchi³

et al. 2010

AJNR Am J Neuroradiol

View full text Add to dashboard Cite

show abstract

“…IgG4‐related IPTs are well known to occur in some head and neck sites including the salivary gland, lacrimal glands and pituitary gland . Other reported sites include nose/paranasal sinus , intracranial/dural sites and parapharyngeal space . IgG4‐related IPT of the trigeminal nerve without involvement of other CNS sites has also been reported by Katsura et al .…”

Section: Introductionmentioning

confidence: 61%

IgG4 Overexpression Is Rare in Meningiomas with a Prominent Inflammatory Component: A Review of 16 Cases

et al. 2014

View full text Add to dashboard Cite

Meningiomas with prominent inflammation are traditionally classified as "lymphoplasmacyte-rich meningioma" (LPM). Both inflammatory and neoplastic meningeal proliferations have recently been linked to IgG4 disease, although a potential association with LPM has not been previously explored. Sixteen meningiomas with inflammatory cells outnumbering tumor cells were further characterized by CD3, CD20, CD68 and/or CD163, CD138, kappa, lambda, IgG and IgG4 immunostains. There were 11 female and 4 male patients, ranging from 22 to 78 (median 59) years of age. Tumors consisted of 10 World Health Organization (WHO) grade I, 5 grade II and 1 grade III LPMs. Immunohistochemically, the most numerous cell type was the macrophage in all cases followed by CD3-positive T cells and fewer CD20-positive B cells. Plasma cells ranged from moderate-marked (N = 5) to rare (N = 7), or absent (N = 4). Maximal numbers of IgG4 plasma cells per high power field (HPF) ranged from 0 to 32, with only two cases having counts exceeding 10/HPF. The IgG4/IgG ratio was increased focally in only two cases (30% and 31%). Additionally, plasma cells represented only a minor component in most examples, whereas macrophages predominated, suggesting that "inflammation-rich meningioma" may be a more accurate term. The inflammatory stimulus for most cases remains to be elucidated.

show abstract

“…The skull base IPT typically presents with headache, and/or cranial nerve palsy. 4 Our patient presented with left-sided headaches and facial nerve palsies as the lesion was located in the left middle cranial fossa and had invaded the petrous bone and clivus. Cranial nerve palsies are most often due to the aggressive, invasive nature of skull base IPT.…”

Section: Discussionmentioning

confidence: 83%

Inflammatory Pseudotumor of the Skull Base Involving Fissura Petrooccipitalis: A Rare Case with Challenging Diagnosis

Huang¹,

Liu²,

Liang³

2011

Skull Base Rep

View full text Add to dashboard Cite

Inflammatory pseudotumor (IPT) is a benign entity that may present as a solid mass mimicking a malignant neoplasm. Histologically, they are composed of varying proportions of myofibroblastic spindle cells, lymphocytes, and plasma cells. Skull base IPT is rare and usually occurs in adults with no sex predilection. The skull base IPT typically presents with headache, and/or cranial nerve palsy. There is no consensus regarding treatment of skull base IPT due to its rarity. Surgical resection and corticosteroid therapy have generally been used. The preoperative diagnosis of skull base IPT is usually difficult due to its nonspecific clinical and radiologic features. We report a case of a 42-year-old woman with IPT originating from the skull base. To our knowledge, this is the first case of IPT invading fissura petrooccipitalis. When a mass in the skull base appears hypointense on T2-weighted imaging with aggressive growth and bony destruction, IPT should be considered in the differential diagnosis.

show abstract

Inflammatory pseudotumor of the parapharyngeal space: A case report

Cited by 29 publications

References 13 publications

IgG4-Related Inflammatory Pseudotumor of the Trigeminal Nerve: Another Component of IgG4-Related Sclerosing Disease?

IgG4-Related Inflammatory Pseudotumor of the Trigeminal Nerve: Another Component of IgG4-Related Sclerosing Disease?

IgG4 Overexpression Is Rare in Meningiomas with a Prominent Inflammatory Component: A Review of 16 Cases

Inflammatory Pseudotumor of the Skull Base Involving Fissura Petrooccipitalis: A Rare Case with Challenging Diagnosis

Contact Info

Product

Resources

About