Inflammatory Pseudotumor of the Orbit*

Lewis, Philip M.

doi:10.1016/s0002-9394(38)91848-3

Cited by 6 publications

(4 citation statements)

References 2 publications

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“…Clinical presentation can vary from slow growth with minimal mass effect, to bony destruction that can mimic malignancy. This entity was first described in the orbit by Birch-Hirschfield in 1905 [4]. , 5, 7, 9, 15, 17].…”

Section: Commentmentioning

confidence: 99%

“…Histologically, they reveal a dense chronic inflammatory infiltrate in a fibrous background and an abundance of plasma cells and/or histiocytes. While the pathogenesis is not entirely known, many features of IPT can be related to production of inflammatory cytokines that sometimes can occur following surgery or even minor trauma [4][5][6][7][8]. Their occurrence is well-documented in the presence of another malignancy or secondary to multiple infectious agents [1,5,7,9].…”

Section: Introductionmentioning

confidence: 99%

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Myocbacterium-Avium Intracellulare Associated Inflammatory Pseudotumor of the Anterior Nasal Cavity

Ilyas

Youssef

Chaudhary

et al. 2011

Head and Neck Pathol

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In this case report, we describe an unusual case of mycobacterial associated inflammatory pseudotumor that occurred in a patient with a previous history of cocaine abuse. We discuss inflammatory pseudotumor (IPT) in general and emphasize the rare entity where an associated mycobacterial infection is seen. The histogenesis is not yet completely understood. The lesion can pose challenges for practicing pathologists and a misdiagnosis of malignancy can occur at multiple facets. A discussion about the differential diagnosis and clues to make the distinction is presented. In addition to spindle cell proliferation, the presence of a background of mixed inflammatory cell infiltrate and foamy macrophages are clues to make the diagnosis. In the case of mycobacteria associated IPT, Acid Fast Bacilli (AFB) stains will easily highlight the organisms confirming the diagnosis.

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Section: Commentmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Myocbacterium-Avium Intracellulare Associated Inflammatory Pseudotumor of the Anterior Nasal Cavity

Ilyas

Youssef

Chaudhary

et al. 2011

Head and Neck Pathol

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“…However the symptoms of orbital pain and headache were considered to be of inflammatory etiology [10][11][12][13][14]. Finally, the results from surgery of the orbit and the response to a therapeutic trial of steroids clinched the diagnosis in favor of inflammatory pseudotumor [18][19][20][21].…”

Section: Discussionmentioning

confidence: 99%

A Case Study on Idiopathic Orbital Pseudotumor: Surgery and Steroid Treatment

Zhu¹,

Zhan²,

Wang³

et al. 2015

Trop. J. Pharm Res

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This is a case study of five isolated orbital nerve inflammatory pseudotumor cases presenting with protrusion and visual acuity of the right eye. Optic disk edema was observed by ophthalmoscopy. Plain and contrast-enhanced magnetic resonance imaging (MRI) were used to examine the orbital fat and enlargement of the right optic nerve sheath along with orbital magnetic resonance imaging diagnostic test. The visual acuity (VA) of all the admitted patients was 1.5/20. All the patients reported attacks of retrobulbar pain and severe headache at fairly regular intervals. The patients on clinical examination were found to have protrusion, reduced visual acuity of the right eye with an ipsilateral afferent pupillary defect. There was no motility of the right eye and the exophthalmos of the right part was 27 mm. On examination, patients were diagnosed to have idiopathic orbital inflammation and received steroid therapy for 6 months. Thereafter, patients received surgical treatment to remove the superior wall of the orbit followed by cortisone therapy for a further 6 months. The follow-up examination of the patients for one year revealed a gradual improvement in the vision of all the patients. The VA of the right eye for all the patients was 6/20, and the exophthalmos was now around 19 mm. Thus, a dramatic response to surgery and steroid treatment was observed in all the patients.

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“…Первые описания воспалительных псевдоопухолей встречаются с начала XX века (P. Lewis, 1937) и касаются поражения глазной орбиты [5]. Этиология заболевания до настоящего времени не установлена.…”

Section: обсуждение (с обзором литературы)unclassified