Inflammatory pseudotumor of the liver

Abstract

Inflammatory pseudotumors (plasma cell granulomas) are localized lesions consisting of a fibrous stroma, chronic inflammatory infiltrate with a predominance of plasma cells, and an absence of anaplasia, which can mimic malignant disease by their gross appearance. Reported in many sites, they are most frequently described in the lung. Twelve cases involving the liver and biliary tract have previously been reported. Here, a 77-year-old man who presented with fever and malaise was found to have a lesion in the left lobe of the liver, which, on exploration, was found to be an inflammatory pseudotumor. This patient, and each of those previously reported, has recovered uneventfully. Because of the benign course of this lesion, hepatectomy should be considered only in those instances in which the mass effect of the lesion is producing symptoms or in those cases in which a firm histologic diagnosis cannot be made preoperatively or by frozen section intraoperatively.

Multiple inflammatory pseudotumors mimicking liver metastasis from colon cancer: Report of a case

“…On the other hand, microorganisms were not identified by culture or histopathological examination in the majority of cases, including ours. Although Klebsiella 8,9 was reported in two cases, and Escherichia coli 10 and Gram-positive cocci 11 were reported in one case each, respectively, it remains uncertain whether these bacteria caused primary infections or resulted from secondary infections. These details are unknown.…”

“…The patient had never been outside of Japan. After his last operation, he suffered from an intermittent fever for 10 days and underwent incision and drainage for a subcutaneous abscess on postoperative day 10. He stated that no other abnormal fevers had developed in the past year.…”

Inflammatorischer pseudotumor der leber ?seltene differentialdiagnose einer unklaren hepatischen raumforderung Fallbericht und literaturbersicht

“…Bei unserem Patienten zeigten sich keine Zeichen eines Ikterus, die anderen aufgeftihrten, sehr unspezifischen Parameter lagen jedoch alle vor. Standiford et al[59] beschrieben den Nachweis von E. coli aus einem inflammatorischen Pseudotumor, in unserem Fall lag eine E.-coliSepsis ungekl~irten Ursprungs vor.Zu diskutieren ist im vorliegenden Fall eine sekund~tr infizierte gr6gere Leberzyste oder ein vorbestehendes Hamangiom, welches unter antibiotischer Therapie eine Transformation zu einem inflammatorischen Pseudotumor der Leber erfahren hat.…”

Liver inflammatory pseudotumor or parasitic granuloma?

“…Infection was considered as a possible etiology [2] . Only two cases with organisms were reported: Escherichia coli was detected in one case [3] , and Gram-positive cocci in the other [4] . Other suggested mechanisms include an immune reaction, liver hemorrhage and necrosis, occlusive phlebitis of hepatic veins, and local reaction to biliary tract [5] .…”