Inflammatory Myofibroblastic Tumour of the Extrahepatic Bile Ducts: An Unusual Cause of Obstructive Jaundice in Children

Buyukyavuz, Ilker; Karnak, İbrahìm; Haliloğlu, Mithat; Me, Senocak

doi:10.1055/s-2003-44736

Cited by 5 publications

(1 citation statement)

References 11 publications

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“…In nationwide survey of Korean children, acquired biliary diseases and congenital hepatobiliary diseases were 7.6% and 12.6% of total hepatobiliary diseases respectively [ 11 ]. Therefore, it is important to define abnormal bile duct dilatation because of its possible association with congenital malformation and pathologic conditions, such as infection, calculi, biliary dysfunction, and malignancy [ 6 12 13 14 15 16 ].…”

Section: Discussionmentioning

confidence: 99%

Asymptomatic Bile Duct Dilatation in Children: Is It a Disease?

Son

Lee

Koh

et al. 2015

Pediatr Gastroenterol Hepatol Nutr

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PurposeBile duct dilatation is a relatively common sonographic finding; nevertheless, its clinical significance in children is controversial because little research has been done in the area. Therefore, we investigated the natural course and clinical significance of biliary duct dilatation in children.MethodsWe performed a retrospective study of 181 children (range, 1-day-old to 17-year-old) in whom dilatation of the intrahepatic duct and/or common hepatic duct and/or common bile duct was detected by abdominal ultrasonography at the Severance Children's Hospital between November 2005 and March 2014. We reviewed and analyzed laboratory test results, clinical manifestations, and clinical course in these patients.ResultsPediatric patients (n=181) were enrolled in the study and divided into two groups. The first group included 59 subjects, without definitive cause of bile duct dilatation, who did not require treatment; the second group included 122 subjects, with definitive cause of bile duct dilatation or underlying biliary disease, who did require treatment. In the first group, 24 patients (40.7%) showed spontaneous resolution of bile duct dilatation, 20 patients (33.9%) showed no change, and 15 patients (25.4%) were lost to follow-up. In the second group, 31 patients were diagnosed with choledochal cysts, and 91 patients presented with biliary tract dilatations due to secondary causes, such as gallbladder or liver disease, post-operative complications, or malignancy.ConclusionBiliary dilatation in pediatric patients without symptoms, and without laboratory and other sonographic abnormalities, showed a benign clinical course. No pathologic conditions were noted on follow-up ultrasonography.

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