Inflammatory Myofibroblastic Tumor of the Bladder in a 3-Year-old Boy

Lecuona, Angus; Wyk, Abraham Christoffel van; Smit, S.; Zarrabi, Amir; Heyns, Chris F.

doi:10.1016/j.urology.2011.04.052

Cited by 15 publications

(21 citation statements)

References 16 publications

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“…Although some cases of IMT are considered to represent an inflammatory response to infection, trauma or surgery, 8 the etiological factors are not clear. We reviewed 17 cases of IMT of the bladder (Table 1); [9][10][11][12][13][14][15][16][17][18][19][20] patients' ages ranged from 3 to 72 years (mean 37) and males were represented slightly more than females (ratio 9:8). The most common symptom of IMT is hematuria.…”

Section: Case Reportmentioning

confidence: 99%

Inflammatory myofibroblastic tumor of the bladder: case report and review of the literature

Wang

et al. 2013

CUAJ

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Inflammatory myofibroblastic tumour (IMT) is a rare tumour with malignant potential, and has been described in many major organs. However, bladder location is very uncommon. We report the case of a 23-year-old woman who presented with painless gross hematuria for 2 weeks. Contrast-enhanced computed tomography revealed a bladder tumour. The patient underwent an open partial cystectomy and the final pathologic diagnosis was IMT of bladder. Typical IMTs can be locally aggressive, therefore close follow-up is necessary.

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Section: Case Reportmentioning

confidence: 99%

Inflammatory myofibroblastic tumor of the bladder: case report and review of the literature

Wang

et al. 2013

CUAJ

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“…Some microbiological agents and autoimmune diseases were blamed, but are not the yet clearly identified etiology of IMT. For now, the etiology of IMTs remains unclear [1].…”

Section: Discussionmentioning

confidence: 99%

“…It has been described in most organ systems; however IMT of the urinary bladder is a very uncommon spindle cell tumor, which has an undetermined malignant potential. It is often mistaken for sarcoma of the bladder and because the former can be managed with a bladder-preserving approach, i.e., transurethral resection (TUR) or partial cystectomy, distinguishing it from the latter is of critical importance [1] [2].…”

Section: Introductionmentioning

confidence: 99%

Inflammatory Myofibroblastic Tumor of the Urinary Bladder—A Case Report with Review of Literature

Deshmukh¹,

Pagey²,

Galani³

et al. 2014

OJPathology

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Inflammatory myofibroblastic tumor (IMT) is a rare neoplasm with unknown malignant potential that has been described in most organ systems. We herein present a case of a young female who presented with macroscopic hematuria. An IMT of the urinary bladder which was not suspected after clinical, radiological and surgical work-up was diagnosed microscopically and confirmed by immunohistochemistry. A close clinical follow-up is recommended because of the unknown biological behavior of this tumor. A brief review of literature is also presented here.

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“…Most IMTs occur in the lungs and airways of young patients. However, other organs, including mesentery, omentum, stomach, small intestine, large intestine, mediastinum, retroperitoneum, liver and bladder, have been documented (1)(2)(3)(4)(5)(6)(7)(8)(9)(10)(11). Among these extrapulmonary IMTs, 43% arise in the mesentery and omentum (29).…”

Section: Discussionmentioning

confidence: 99%

“…IMT used to be considered as an inflammatory pseudotumor, xanthogranuloma, plasma-cell granuloma, plasma-cell pseudotumor or an inflammatory myofibroblastic tumor. IMT commonly occurs in the lung, mesentery, omentum and retroperitoneum, but it may also be observed in the extremities, head and neck region, liver, spleen, thyroid, gastrointestinal tract, genitourinary tract and other systems (1)(2)(3)(4)(5)(6)(7)(8)(9)(10)(11). The tumors usually follow a benign course, but recurrences have been documented in up to 25% of cases.…”

Section: Introductionmentioning

confidence: 99%

Primary inflammatory myofibroblastic tumor of the breast with rapid recurrence and metastasis: A case report

Zhao¹,

Wang

et al. 2012

Oncology Letters

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Abstract. Primary inflammatory myofibroblastic tumor (IMT) of the breast is extremely rare; only 19 cases have been reported in the English literature. In the present study, we present a case of IMT in a 56-year-old female patient who was admitted to our hospital due to a mass found in her right breast. Mammogram and ultrasound revealed a well-circumscribed mass and surgery was performed. Histopathologically, the lesion was composed of spindle and inflammatory cells, including plasma cells and lymphocytes. Mitotic figures were not observed. Immunohistochemically, the tumor cells were positive for SM-actin, anaplastic lymphoma kinase (ALK) and vimentin and focal positive for desmin, but negative for NSE, S-100, CD117, CD34, NF, CD21, CD35 and CD68. Thus, we made a diagnosis of IMT and advised regular follow-up. However, the patient had local recurrence and metastasis to the left groin area 3, 7 and 10 months after the initial surgery. Notably, the histopathological characteristics of the recurrent and metastatic foci were similar to those of the initial specimen, but mitotic figures were clearly observed. Thus, we conclude that IMT shows occasionally malignant biological behavior although it is a neoplasm of intermediate biological potential that frequently recurs and rarely metastasizes. We advise that clinical physicians should regularly follow up patients after focal resection for IMT.

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Inflammatory Myofibroblastic Tumor of the Bladder in a 3-Year-old Boy

Cited by 15 publications

References 16 publications

Inflammatory myofibroblastic tumor of the bladder: case report and review of the literature

Inflammatory myofibroblastic tumor of the bladder: case report and review of the literature

Inflammatory Myofibroblastic Tumor of the Urinary Bladder—A Case Report with Review of Literature

Primary inflammatory myofibroblastic tumor of the breast with rapid recurrence and metastasis: A case report

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