Inflammatory Myofibroblastic Tumor of Genitourinary Tract Beyond Collecting System

Abstract

Inflammatory myofibroblastic tumor (IMT) rarely arises in genitourinary tract especially beyond collecting system, which determines the unspecific clinic symptoms and sometimes can mimic malignancy. Therefore, IMT's diagnosis may usually be a pitfall. This case report characterizes a 35-year-old woman with a history of lower quadrant lasting pain followed by fever. Furthermore, radiologic examinations revealed that there were 2 lesions located in left adrenal area and left renalis. Owing to the anatomic complexity, the surgical resection was not complete. The pathologic diagnosis of the lesions was IMT. Adjuvant nonsteroids anti-inflammatory drugs were administrated after the operation. The symptoms were controlled finally and no further growing lesion was observed during a 1-year follow-up.Inflammatory myofibroblastic tumor is rare in genitourinary tract beyond the collecting system. Diagnosis should be based on histopathology. Presently, the authors report this rare case with the aim to share the experience regarding differential diagnosis and therapy.

Inflammatory Myofibroblastic Tumor of the Trachea: A Case Report and Review of the Literature

“…IMT is a rare mesenchymal tumor that is still not fully understood in terms of its etiology and pathogenesis [6,7]. According to several studies conducted in recent years, infection, surgery, trauma and chromosomal variations may have a role in the development of IMT and there are localized deviations in chromosome 2 and 9 [6,8].…”

“…According to several studies conducted in recent years, infection, surgery, trauma and chromosomal variations may have a role in the development of IMT and there are localized deviations in chromosome 2 and 9 [6,8].…”

“…Although IMT can occur in many different anatomical regions, it is most frequently seen in the lungs of the respiratory system followed by abdominopelvic region and retroperitoneum [5,6,10]. Tracheal involvement is rare.…”

“…Since clinical and radiological findings are nonspecific in the diagnosis of IMTs, the definitive diagnosis is based on histopathological examination of the excised material [6,13]. Histologically; infiltration of inflammatory cell consisting of plasma cells, lymphocytes and eosinophils that are accompanying the proliferation of myofibroblasts is observed [1,5].…”

A rare case of inflammatory myofibroblastic tumor of the vulva in a newborn

“…Inflammatory myofibroblastic tumor (IMT) is a rare mesenchymal tumor with unknown etiology [1] . The lungs, liver, and gastrointestinal tract are the most common sites for IMT; however, in rare cases, IMT can affect the genitourinary tract [1] .…”