Inflammatory Bowel Disease

Galland, Leo

doi:10.1016/b978-1-4160-2954-0.50053-3

Cited by 15 publications

(19 citation statements)

References 153 publications

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“…In addition, diarrhea causes the loss of electrolytes, including calcium, magnesium, and zinc. Magnesium deficiency is common and related to gastrointestinal loss and inadequate intake 26. Zinc loss is correlated with the volume of diarrhea, and the loss of zinc increases with steatorrhea, as are the losses of other divalent cations (e.g., calcium, magnesium, copper) and fat soluble vitamins 25.…”

Section: Discussionmentioning

confidence: 99%

Nutritional Status and Growth in Korean Children with Crohn’s Disease: A Single-Center Study

Song¹,

Kim²,

Oh³

et al. 2014

Gut Liver

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Background/AimsMalnutrition and growth retardation are important issues in treating pediatric Crohn’s disease (CD). Thus, we aimed to investigate the prevalence of various nutritional and growth parameters at the time of diagnosis in Korean children with CD.MethodsSeventy-one children (<18 years) were enrolled. We analyzed the Z-scores of height-for-age (HAZ), weight-for-height (WHZ), body mass index for age (BMIZ), bone mineral density for age (BMDZ), and the biochemical markers measured at the time of diagnosis.ResultsAt diagnosis, HAZ <−2 was observed in three patients (4%), WHZ <−2 in 20 patients (28%), BMIZ <−2 in 19 patients (27%), and BMDZ <−2 in 11 patients (18%). The HAZ was significantly lower in females and patients with extraintestinal manifestations, and the WHZ and BMIZ were significantly lower in patients with stricturing and penetrating disease. Subnormal serum levels were highly prevalent for hemoglobin, albumin, iron, ferritin, calcium, magnesium, folate, vitamin B12, and zinc. There was a significant correlation between nutritional status, growth retardation, and disease activity.ConclusionsAbnormal nutritional status was highly prevalent in Korean children with CD at the time of diagnosis and was associated with the extent, behavior, and activity of the disease.

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Section: Discussionmentioning

confidence: 99%

Nutritional Status and Growth in Korean Children with Crohn’s Disease: A Single-Center Study

Song¹,

Kim²,

Oh³

et al. 2014

Gut Liver

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“…44 Slippery elm is reported by some to soothe inflammation of the gastrointestinal tract and associated frequency and sensitivity 45 A combination of zinc and magnesium (along with vitamin B 6 as coenzyme to assist their assimilation) is recommended to promote a healthy gut mucosa, immune function, and normal gut motility. [46][47][48] We especially encourage supplementation in patients with chronic diarrhea, which depletes these elements. 17,49 Postmenopausal women with PSBD may benefit from a topical estrogen to alleviate symptoms of urogenital atrophy.…”

Section: Supplementsmentioning

confidence: 99%

Practical Strategies for Treating Postsurgical Bowel Dysfunction

Sloots

Bartlett²

2009

Journal of Wound, Ostomy &Amp; Continence Nursing

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Postsurgical bowel dysfunction is a potential complication for patients undergoing ileoanal anastomosis, restorative proctocolectomy, and low anterior anastomosis. In our setting, these patients are referred to the Anorectal Physiology Clinic at the Townsville Hospital, Queensland, for comprehensive behavioral therapy. The goals of the therapy are as follows: improve stool consistency, improve control over stool elimination, decrease fecal frequency and rectal urgency, fecal continence without excessive restrictions on food and fluid intake, and increase quality of life. This article outlines our holistic approach and specific treatment strategies, including assessment, education, support and assistance with coping, individualized dietary and fluid modifications, medications, and exercise. Biofeedback is used to help patients improve anal sphincter and pelvic floor muscle function and bowel elimination habits. Information on the biofeedback component of the treatment program will be described in a subsequent article.

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“…Parenteral Mg requirements in patients with IBD are at least 120 mg/day or more depending upon fecal or stomal losses. Oral requirements may be as great as 700 mg/day depending on the severity of malabsorption [20] .…”

Section: Magnesium Deficiencymentioning

confidence: 99%

“…Symptoms of Mg deficiency include cramps, bone pain, delirium, acute crises of tetany, fatigue, depression, cardiac abnormalities, urolithiasis, impaired healing and colonic motility disorders [20] . Decreased physical performance is a frequent complaint in CD.…”

Section: Magnesium Deficiencymentioning

confidence: 99%

Iron Deficiency, Zinc, Magnesium, Vitamin Deficiencies in Crohn's Disease: Substitute or Not?

Kruis

Nguyen²

2016

Dig Dis

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Inflammatory bowel disease (IBD) is characterized by inflammatory reactions, complications, extraintestinal manifestations and a loss of intestinal functions, for example, failures of absorption and secretion. According to intestinal dysfunction, a wide array of pathogenetic pathways is existing leading to iron deficiency and numerous vitamins as well as trace element deficiencies. Complications, symptoms and signs of those deficiencies are common in IBD with varying degrees of clinical significance. This review focuses on selected micronutrients including iron, zinc, magnesium and some vitamins. Epidemiology with respect to IBD, pathophysiology, diagnosis and clinical aspects are addressed. Finally, some suggestions for treatment of deficient situations are discussed. In conclusion, some micronutrients have significant impact on complications and quality of life in IBD. Deficiencies may even influence the course of the disease. Those deficiencies should be thoroughly supplemented.

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Inflammatory Bowel Disease

Cited by 15 publications

References 153 publications

Nutritional Status and Growth in Korean Children with Crohn’s Disease: A Single-Center Study

Nutritional Status and Growth in Korean Children with Crohn’s Disease: A Single-Center Study

Practical Strategies for Treating Postsurgical Bowel Dysfunction

Iron Deficiency, Zinc, Magnesium, Vitamin Deficiencies in Crohn's Disease: Substitute or Not?

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