Inflammatory bowel disease and gastrointestinal disorders

A Micro‐longitudinal Approach to Measuring Medication Adherence in Pediatric Inflammatory Bowel Diseases

“…Consequences include disease relapse (3), increased healthcare utilization (4), and treatment escalation (5). Nonadherence may result from the complexity of the regimen (6), which consists of multiple medications across dosing schedules and formulations (7). With the introduction and common use of injectable and intravenous biologic therapies over the past 15 years (8), fewer youth with IBD are prescribed daily oral medications alone.…”

“…Pediatric IBD adherence research has utilized objective (eg, pill counts, electronic monitoring, bioassays) and subjective measures (eg, validated measures, visual analog scales) to examine nonadherence (7,9). Although objective measures are considered the ''gold standard,'' they are not useful across medication regimens broadly.…”