Inflammatory Biomarkers in Febrile Seizure: A Comprehensive Bibliometric, Review and Visualization Analysis

Abstract

Background: The associations between inflammatory markers and many diseases have been the subject of many articles and reviews. This study presents a comprehensive bibliometric, review and visualization analysis of inflammatory biomarkers (IB) in the context of febrile seizure (FS) patients. Methods: The study focused on the IB in FS using (1) bibliometric analysis-specific indicators and maps in order to analyze and present the network of authors, journals, universities and countries, (2) automated literature screening and unsupervised clustering approach for filtering and topic cluster identification. Results: We conducted a literature mining search on FS research, specifically IB in the context of FS, using automated tool VOSViewer. The presentation and discussions on the resulted bibliometric maps and topic clusters offer a comprehensive overview, status and leading trends in existing research on inflammatory biomarkers in FS. Conclusion. The analysis using bibliometric methods and review with graphical presentations can be very useful in investigating and better understanding the relationship between FS and IB.