Inflammatory abdominal aortic aneurysm: Predictors of long-term outcome in a case-control study

Kalko, Yusuf; Başaran, Murat; Ünal, Aydın; Kafa, Ülkü; Kösker, Taylan; Ozcalıskan, Ozerdem; Yücel, Erdal; Yaşar, Tahsin

doi:10.1016/j.surg.2006.04.007

Cited by 22 publications

(2 citation statements)

References 16 publications

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“…There is strong evidence that even subtle elevations in creatinine can translate into adverse perioperative events. 20,21 However, this finding is more meaningful in the TAG group as data for the open surgical patients did not always include creatinine values. We interpret these results to indicate that in patients with even subtle elevations in creatinine renal dysfunction may be a marker for systemic vasculopathy and that these patients should be warned that they may have a higher incidence of complications.…”

Section: Discussionmentioning

confidence: 97%

Predictors of morbidity and mortality with endovascular and open thoracic aneurysm repair

Dillavou

Makaroun

2008

Journal of Vascular Surgery

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Elevated creatinine levels and symptomatic aneurysms predict morbidity and mortality, respectively, regardless of repair type. Male gender predicted death after open surgery, and since most deaths (9 of 12) were in this group, male gender predicted death overall, despite women's more difficult endovascular TAA repairs as evidenced by longer procedure times and higher vascular complication rates. All major adverse events and paraplegia were more common for open surgery patients.

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Section: Discussionmentioning

confidence: 97%

Predictors of morbidity and mortality with endovascular and open thoracic aneurysm repair

Dillavou

Makaroun

2008

Journal of Vascular Surgery

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“…Traditionally, Staphylococcus, Streptococcus, and Salmonella species have been considered the most frequent bacteria causing MAA, but the spectrum of other organisms is widening [ 6 ]. MAA and InflAAA make up about 1.3% and 4–7% of all AAAs, respectively [ 7 , 8 ]; diagnosis is based on a combination of clinical presentation, laboratory findings, and characteristics on computed tomography (CT) angiography [ 3 , 7 , 9 ]. A typical feature on imaging is the “the mantle sign”; a thickened contrast-enhancing aortic wall resulting from chronic inflammation in the perianeurysmal space [ 10 ].…”

Section: Introductionmentioning

confidence: 99%

Mycotic abdominal aortic aneurysm caused by Borrelia afzelii: a case report

et al. 2022

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Background Inflammatory aneurysms and mycotic aneurysms make up a minority of abdominal aortic aneurysms. Mainly autoimmune mechanisms are proposed in the pathogenesis of inflammatory aneurysms, and it is not routine to check for infectious agents as disease culprits. Case presentation A 58-year-old European male with complaints of abdominal and back pain for 8 weeks was admitted after a semi-urgent computed tomography scan revealed an 85 mm inflammatory abdominal aortic aneurysm. The patient had normal vital signs, slightly elevated inflammatory markers, and mild anemia on admission. Clinical examination revealed a tender pulsating mass in his abdomen. His clinical condition was interpreted as impending rupture and urgent repair of the aneurysm was deemed necessary. Due to the patient’s relatively young age and aneurysm neck morphology, open aortic repair was preferred. Preoperatively, the aneurysm appeared inflamed, with fibrous wall thickening and perianeurysmal adhesions. Aneurysm wall biopsies were sent to histopathological and microbiological diagnostics. Routine cultures were negative, but 16S rRNA gene real-time polymerase chain reaction was positive and Borrelia afzelii was identified by DNA sequencing of the polymerase chain reaction product. B. afzelii was also identified by sequencing the polymerase chain reaction product of a Borrelia-specific groEL target. Immunoglobulin G and M anti-Borrelia antibodies were present on serological analysis. Histopathological analysis displayed loss of normal aortic wall structure and diffuse infiltration of lymphocytes and plasma cells. The patient had an uneventful recovery and was discharged after 1 week to a regional rehabilitation facility. Though the patient fares clinically well and inflammatory markers had normalized, antimicrobial treatment with doxycycline continues at 3 months follow-up due to remaining radiologic signs of inflammation. Conclusions Borrelia infection in the setting of acute aortic pathology is a rare entity. To our knowledge, this is the first case report to demonstrate a mycotic abdominal aortic aneurysm as a rare manifestation of Lyme disease. Aortic wall biopsies and real-time polymerase chain reaction analysis of the specimen were essential for accurate diagnosis. This finding may contribute to the understanding of the etiology of inflammatory aneurysmal disease and abdominal aneurysms in general.

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Abdominal Aortic Aneurysm

Bessen¹

2010

Rosen's Emergency Medicine – Concepts and Clinical Practice

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Inflammatory abdominal aortic aneurysm: Predictors of long-term outcome in a case-control study

Cited by 22 publications

References 16 publications

Predictors of morbidity and mortality with endovascular and open thoracic aneurysm repair

Predictors of morbidity and mortality with endovascular and open thoracic aneurysm repair

Mycotic abdominal aortic aneurysm caused by Borrelia afzelii: a case report

Abdominal Aortic Aneurysm

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