Inflammation and kidney injury attenuated by prior intake of Brazil nuts in the process of ischemia and reperfusion

Abstract

In experimental IR, the damage can be minimized with a prior low-dose intake of BN, improving inflammation, injury, and cell death.

Renoprotective effect of vildagliptin following hepatic ischemia/reperfusion injury

“…The existence of a link between the TGF-b/smad2/3 signaling pathway and inflammation was reported by a recent study that observed an activation of the TGFb/smad2/3 signaling in a mouse model of bronchial asthma with inflammatory reaction confirming that this pathway plays role in the inflammation [36]. The TGF-b was considered as a potent inflammatory mediator for different immune cell types like neutrophils and other PMN cells [37] and its release was documented after the renal IR process [38]. The activation of the infiltrated inflammatory cells after tissue injury produced ROS and induced fibrogenic cytokines if inflammation persists and not resolved [39].…”

Características botânicas, importância socioeconômica e usos em saúde da castanha-do-Brasil (Bertholletia excelsa): uma revisão

“…Sua maior concentração está na porção brasileira, principalmente no planalto que separa a bacia formada pelos afluentes do baixo Amazonas, alto Tocantins e alto Moju, e em terras altas ao norte do Rio Jarí, no estado do Pará e nos estados do Acre até o alto Beni e no Amapá (CURY et al, 2018). No Amazonas a castanheira é distribuída uniformemente em todo território, porém sua ocorrência é mais frequente ao longo das calhas dos rios Madeira, Purus e Solimões (CARDOSO et al, 2017).…”