Inflammation and Fibrosis in Sleep-Disordered Breathing after Acute Myocardial Infarction
Jan Pec,
Stefan Buchner,
Henrik Fox
et al.
Abstract:Background: After acute myocardial infarction (AMI), inflammatory processes promote tissue remodeling at the infarct site. Procollagen III amino-terminal propeptide (PIIINP) is a circulating biomarker of type III collagen synthesis that has been shown to be associated with changes in left ventricular ejection fraction (LVEF) and predicts the occurrence of heart failure after AMI. We hypothesize that sleep-disordered breathing (SDB) promotes inflammation and myocardial fibrosis, leading to reduced myocardial sa… Show more
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