2011
DOI: 10.1080/ac.66.5.2131091
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Infl uence of cardiac rehabilitation on natriuretic peptides

Abstract: Basal levels of peptides did not change significantly after the programme but rose with the workout, especially in patients with left ventricular dysfunction. Patients with higher baseline levels obtained greater functional recovery. We conclude that NT-proBNP measurement may be useful in selecting patients to perform a cardiac rehabilitation programme.

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“…Patients who have undergone open heart surgery experience a similar increase, although they have higher pre-test levels [24]. Variation on natriuretic hormone measurements in a population of patients with heart disease is about 20% [25] According to these studies, we calculated that we could detect a 30% difference between the two groups (with expected lower increase in the group randomized to closure of the LAA) by including 42 patients with 90% power and a 5% risk of type 2 error. With 80% power and the same significance level, according to the variation observed in MR-proANP measurements [22], we calculated that we needed to include eight patients in each group and we planned to include 10 patients in each group.…”
Section: Statisticsmentioning
confidence: 99%
“…Patients who have undergone open heart surgery experience a similar increase, although they have higher pre-test levels [24]. Variation on natriuretic hormone measurements in a population of patients with heart disease is about 20% [25] According to these studies, we calculated that we could detect a 30% difference between the two groups (with expected lower increase in the group randomized to closure of the LAA) by including 42 patients with 90% power and a 5% risk of type 2 error. With 80% power and the same significance level, according to the variation observed in MR-proANP measurements [22], we calculated that we needed to include eight patients in each group and we planned to include 10 patients in each group.…”
Section: Statisticsmentioning
confidence: 99%