1993
DOI: 10.1177/019459989310800213
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Infiltrative Clival Pituitary Adenoma of Ectopic Origin

Abstract: An ectopic pituitary adenoma is a rare entity that may occur in several anatomic locations, the sphenoid sinus being the most common. Many of these tumors are amenable to surgical resection by means of a transsphenoidal approach. A more aggressive surgical approach is needed to attempt resection of extensive tumors that involve the clivus and the nasopharynx. Complete resection in these areas cannot always be guaranteed or determined, necessitating postoperative radiotherapy. Many different tumors of the sphen… Show more

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Cited by 51 publications
(22 citation statements)
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“…Neuroembryologically, the origin and pathogenensis of ectopic RCC is a subject of controversy, however, it is not surprising to assume that it is similar to the mechanism for ectopic occurrence of the pituitary adenoma or craniopharyngioma2,5). Ectopic locations include the nasopharynx, the sphenoid sinus, the clivus, and the posterior fossa7,11,15).…”
Section: Discussionmentioning
confidence: 99%
“…Neuroembryologically, the origin and pathogenensis of ectopic RCC is a subject of controversy, however, it is not surprising to assume that it is similar to the mechanism for ectopic occurrence of the pituitary adenoma or craniopharyngioma2,5). Ectopic locations include the nasopharynx, the sphenoid sinus, the clivus, and the posterior fossa7,11,15).…”
Section: Discussionmentioning
confidence: 99%
“…This implies that further study of therapeutic technique may be warranted in this patient group. Although invasion of pituitary tumors into the clivus has been described, [9][10][11][12][13][14][15][16][17][18] mostly in the form of case reports, 7,8,19 to our knowledge, this is the first study designed to systematically define the clinical and histologic correlates of clival invasion on CT in a large patient cohort.…”
mentioning
confidence: 99%
“…Other extracranial sites include the nasal cavity, mid-nasal ductus, nasopharynx (3,28,29), clivus (30)(31)(32)(33)(34)(35), sphenoid, ethmoid, petrous and temporal bone. The majority of the intracranial extrasellar EPAs are located in the suprasellar region (approximately 33%), usually contiguous with the pituitary stalk (28,36).…”
Section: Discussionmentioning
confidence: 99%