“…As has been shown previously, radical resection of locally recurrent disease can achieve longterm survival [4,[13][14][15]24] and should, therefore, be aimed at, even if extended resection (e.g. abdominosacral resection or exenteration) [16,25,26] or flap-reconstruction [27] is required. Sur vival in patients treated with non-radical surgery and patients treated with radiotherapy and/or chemotherapy without surgery was comparable, but was significantly worse in patients not treated with surgery, radiotherapy or chemotherapy.…”