“…Misplaced Central venous cannulation is a common complication faced by anesthesiologist all over the world. Central venous catheter(CVC) have been found to be misplaced in normal or rarely anomalous structures (1)(2)(3)(4). The various sites of CVC malpostion and their clinical features are: carotid artery ( hypotension and hemorrhagic shock); azygos vein ( pleural effusion, pulmonary edema, dyspnea, chest pain, back pain, and cardiac tamponade); persistent leftsided superior vena cava (cardiac tamponade); internal mammary vein ( shoulder or arm pain); vertebral vein ( thrombosis, endothelial damage, and fluid leakage); extradural space (severe back pain); pericardium (hemopericardium, fatal ventricular fibrillation), pleural space (dyspnea, pneumothorax, chest pain, and back pain); mediastinum (Chest pain); thoracic duct(infusion mediastinum and chylothorax) (5).…”