Inferior Petrosal Sinus Sampling Tumor Lateralization and the Surgical Treatment of Cushing Disease: A Meta-Analysis and Systematic Review

Webb, Kevin L.; Hinkle, Mickayla L.; Walsh, Michael T.; Bancos, Irina; Shinya, Yuki; Van Gompel, Jamie J.

doi:10.1016/j.wneu.2023.12.024

Cited by 1 publication

(2 citation statements)

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“…with BIPSS, 53% concordant with magnetic resonance, without association with postoperative remission [27].…”

Section: Accepted Manuscriptmentioning

confidence: 87%

“…An unstimulated gradient between the central and peripheral ACTH > 2, or > 3 after CRH or desmopressin, indicates CD. The reliability of BIPSS in localizing the left/right side of the adenoma within the pituitary gland is poor; a recent meta-analysis reported 69 % correct tumor lateralization with BIPSS, 53 % concordant with magnetic resonance, without association with postoperative remission [27].…”

Section: Bilateral Inferior Petrosal Sinus Sampling (Bipss)mentioning

confidence: 99%

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Subtyping of Cushing’s Syndrome: A Step Ahead

Tizianel,

Barbot,

Ceccato

2024

Exp Clin Endocrinol Diabetes

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Cushing’s Syndrome (CS) is a rare disease due to chronic endogenous cortisol secretion. In the last years, new acquisitions enlarged the spectrum of differential diagnosis, historically divided into ACTH-dependent and ACTH-independent forms. Moreover, the increased awareness of the detrimental cortisol effects on cardiometabolic health and the risk of cardiovascular events lead to increased diagnosis of mild forms, especially in the context of adrenal incidentalomas. We provide and up-to-date narrative review of the most recent literature regarding the challenges of CS diagnosis. After the description of the diagnostic tools available, we describe the characterization of functional non-neoplastic hypercortisolism (formerly known as pseudo-Cushing state), then we report the subtyping of the different conditions of hypercortisolism: the differential diagnosis of ACTH-dependent forms and the management of adrenal hypercortisolism, with peculiar attention to the new genetic classification of adrenal CS, mild autonomous cortisol secretion and bilateral adrenal adenomas.

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“…with BIPSS, 53% concordant with magnetic resonance, without association with postoperative remission [27].…”

Section: Accepted Manuscriptmentioning

confidence: 87%

Section: Bilateral Inferior Petrosal Sinus Sampling (Bipss)mentioning

confidence: 99%