Inferior alveolar nerve block and third-molar agenesis

Swee, Jerry; Silvestri, Anthony R.; Finkelman, Matthew; Rich, Alfred P; Alexander, Stanley A.; Loo, Cheen Y.

doi:10.14219/jada.archive.2013.0132

Cited by 10 publications

(8 citation statements)

References 25 publications

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“…Some mutations have been shown to cause agenesis, but there are currently no known mutations that cause agenesis without other symptoms. While studies have long suggested a genetic component to agenesis (Garn and Lewis 1962;Shimizu et al 2013), environmental disturbances occurring before the M3 initiates have been shown to produce this pathology (Swee et al 2013 Odds ratio of female to male M3 agenesis Bansal, 2012Sandhu and Kaur, 2005Byahatti et al, 2011Ren and Kumar, 2014Shah and Parekh, 2014Garcia−Hernandez and Rodriguez, 2009Nicodemo, 1973Bhowmik, 2013Daito et al, 1992Hellman, 1936Haga et al, 2013Golovcencu and Geletu, 2012Shah and Boyd, 1979Lee et al, 2009Bhutta and Sadozai, 2013Hubenthal, 1989Sonnabend, 1966Raloti et al, 2013Nanda and Chawla, 1959Kirveskari et al, 1978Ghada, 2005Weise and Bruntsch, 1965Sarmiento and Herrera, 2004Garcia−Hernandez et al, 2008Elomaa and Elomaa, 1973Costa et al, 2007Godt and Greve, 1980Celikoglu and Kamak, 2012Celikoglu et al, 2010Krekeler et al, 1974Haga et al, 2013Speckin, 1981Hentisz, 2003Shinn, 1976Oliveira and Serra Negra, 1984Oliveira and Serra Negra, 1976Mok and Ho, 1996Afify and Zawawi, 2012Holzl, 1972Endo et al, 2015Kazanci et al, 2010Thompson et al, 1974Adler and Adler−Hradecky, 1963…”

Section: Discussionmentioning

confidence: 99%

Morphologic and Demographic Predictors of Third Molar Agenesis

Worthington

2015

J Dent Res

105

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We aimed to consolidate all available data on worldwide third molar agenesis frequencies, with a particular emphasis on exploring the factors leading authors to find contradictory results for the demographic and morphologic predictors of this anomaly. A total of 12,376 studies were originally identified, then narrowed down to 1,312 for title/abstract screening. On the basis of our inclusion and exclusion criteria, we selected 92 studies, containing 100 effect sizes and 63,314 subjects, for systematic review and metaregression. The worldwide rate of agenesis was found to be 22.63% (95% confidence interval = 20.64% to 24.76%), although the estimates ranged from 5.32% to 56.0%. Our subgroup analyses revealed that women are 14% more likely than men to have agenesis of ≥1 third molars and that maxillary agenesis was 36% more likely than mandibular agenesis in both sexes. Furthermore, we found that having agenesis of 1 or 2 molars was most common, while agenesis of 3 or 4 molars was least common. Finally, we found large differences among agenesis frequency depending on geographic region. This information is expected to be of use not only to clinicians and patients but also to policy makers, given the implications for third molar extraction protocols.

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Section: Discussionmentioning

confidence: 99%

Morphologic and Demographic Predictors of Third Molar Agenesis

Worthington

2015

J Dent Res

105

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“…Por otra parte, Kim (2007) estudió el efecto citotóxico de distintas soluciones anestésicas utilizadas en odontología (articaína, bupivacaína, levobupivacaína, lidocaína, mepivacaína, prilocaína y procaína) en un linaje celular odontoblast-like (MDPC-23) reportando que bupivacaína induce muerte celular de forma significativa a una concentración de 1000 µM siendo este efecto dosis-dependiente, determinando una dosis letal media de 1200 µM. Swee et al (2013) observaron la relación entre de agenecia de terceros molares mandibulares y aplicación de anestesia troncular a la língula mandibular, en 220 niños de 7 a 12 años de edad, que entre los 2 y los 6 años habían sido sometidos a esta técnica durante procedimientos odontológicos de rutina. Las evaluaciones de desarrollo de tercer molar se realizó mediante examen radiográfico y se consideraron para el estudio niños con evidencia radiográfica de al menos un tercer molar mandibular, encontrando relación significativa entre la administración de anestesia troncular a la língula mandibular y agenesia unilateral de tercer molar mandibular.…”

Section: Discussionunclassified

Anestesia Local Odontológica y su Influencia en Anomalías del Desarrollo Dental: Revisión Sistemática de la Literatura

Fuentes

Curiqueo

Rivera

et al. 2015

Int. J. Odontostomat.

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“…A recent epidemiological study showed that local anesthetics could potentially induce tooth agenesis. 10 Using detailed dynamic cellular energetic analysis, our recent findings suggest that these drugs are able to rapidly induce autophagy in the tooth pulp cells, both in animal models and in cultured human cells. 9 The induced autophagy is due to increased mitochondrial respiration, which is believed to counteract the toxicity of the drugs, that is, a protection mechanism.…”

Section: Drugsmentioning

confidence: 99%