Infektions- und andere entzündliche Erkrankungen des Zentralnervensystems

Huffmann, G

doi:10.1007/978-3-642-71821-2_5

Cited by 5 publications

(2 citation statements)

References 58 publications

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“…Moreover, a temporary increase of cells in the cerebrospinal fluid could be observed again at the same time (see Technical findings). The infectious agent was not found which is not unusual for acute encephalitis (Huffmann, 1988).…”

Section: Discussionmentioning

confidence: 86%

Secondary psychotic symptoms in a patient with biphasic meningo-encephalitis

et al. 1993

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SummaryWe report on the case of a patient who developed an acute meningitis and, after a period of about two weeks, without any neuropsychiatric problems, an acute paranoid-hallucinatory and catatonic syndrome. The symptomatology is discussed, in relation with the diagnostic difficulties of differentiating between a biphasic meningo-encephalitis with an organic psychosis or a first manifestation of an endogenous psychosis.

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Section: Discussionmentioning

confidence: 86%

Secondary psychotic symptoms in a patient with biphasic meningo-encephalitis

et al. 1993

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“…Chlormethiazole was introduced in Germany in 1961 with excellent results in the treatment of alcohol delirium (Athen et al, 1977;Bergener, 1966;Glatt, 1980;Glatt & Frisch, 1969;Huffmann & Leven, 1965;Salum, 1966;Sattes, 1964). Chlormethiazole has additionally been used for hyperactive delirium in geriatrics.…”

Section: Discussionmentioning

confidence: 99%

Chlormethiazole as a hypnotic in elderly patients: A systematic review and meta‐analysis

Al Juburi,

Cramer,

Schaefer

2023

Journal of Sleep Research

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SummaryThe study objective was to estimate the efficacy and safety of chlormethiazole in older adults experiencing insomnia (sleep disorder). We therefore systematically searched Medline, Scopus, the Cochrane Library, PsycINFO, Ovid, ZB MED and PMC through December 2021 for randomized–controlled trials including patients > 60 years old with insomnia treated with chlormethiazole. Standardized mean differences or odds ratios with 95% confidence intervals were calculated for the main outcome parameters: sleep duration, onset of sleep, quality of sleep, adverse events or drop‐out rates compared with placebo and other drugs. Risk of bias was assessed using the Cochrane tool. Eight randomized–controlled trials with 424 patients were included. Chlormethiazole significantly increased the duration of sleep when compared with placebo (standardized mean difference = 0.61; 95% confidence interval = 0.11–1.11; p = 0.02). More patients receiving chlormethiazole had adequate quality of sleep than those receiving other drugs (odds ratio = 1.44; 95% confidence interval = 1.04–1.98; p = 0.03). No differences were found regarding the onset of sleep (standardized mean difference = 1.07; 95% confidence interval = 0.79–1.46; p = 0.65). Drop‐out rates were significantly lower under chlormethiazole treatment when compared with other drugs (odds ratio = 0.51; 95% confidence interval = 0.26–0.99; p = 0.05) and did not differ from placebo treatment (odds ratio = 1.37; 95% confidence interval = 0.23–8.21; p = 0.73). Side‐effects such as “hangover” and daytime drowsiness occurred less frequently during chlormethiazole treatment compared with other drugs in three out of four studies, but differences were not significant (odds ratio = 0.24; 95% confidence interval = 0.04–1.48; p = 0.12). In conclusion, chlormethiazole showed significant effects on the duration and the quality of sleep with better tolerability if compared with other drugs in older adults with insomnia.

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Kraniale Magnetresonanztomographie (MR) und kraniale Computertomographie (CCT) bei Morbus Behçet und Herpesenzephalitis

Pausch¹,

Huffmann²

1989

Verhandlungen Der Deutschen Gesellschaft Für Neurologie

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Infektions- und andere entzündliche Erkrankungen des Zentralnervensystems

Cited by 5 publications

References 58 publications

Secondary psychotic symptoms in a patient with biphasic meningo-encephalitis

Secondary psychotic symptoms in a patient with biphasic meningo-encephalitis

Chlormethiazole as a hypnotic in elderly patients: A systematic review and meta‐analysis

Kraniale Magnetresonanztomographie (MR) und kraniale Computertomographie (CCT) bei Morbus Behçet und Herpesenzephalitis

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