Infektionen durch Methicillin-resistente Staphylococcus aureus (MRSA)

Abstract

The increasing number of complicated soft-tissue or invasive infections caused by methicillin-resistant Staphylococcus aureus (MRSA) is a frequent reason for elaborate treatment regimens. Unidentified MRSA carriers may be the origin of endemic spread to other patients and medical staff. Recently, community-associated cMRSA with particular virulence factors were isolated from persons without the typical history of hospital contacts. Molecular tools for the timely detection of the mecA resistance gene for the identification of MRSA in medical test specimens have become a standard approach in MRSA-related diagnostic procedures. The actual therapy of MRSA infections requires consideration of both the appropriate spectrum of activity and the adequate pharmacological properties of a chosen antimicrobial. Preventive strategies rely on the consistent application of standard hygiene precautions, which have to be supplemented with increased barriers for the isolation of identified MRSA patients.

Methicillin-resistant Staphylococcus aureus among healthcare workers: screening, risk factors and treatment

“…On the other hand, it should be noted that rifampicin should not be used alone for eradicating MRSA infections and colonization. 41 Furthermore, applying adequate interventional modalities can be the key solution against MRSA colonization and can lead to significant eradication of the infection rates. Hand hygiene is an important measure that should be routinely done, however, its efficacy on the barrier functions is still not completely understood.…”

Problematik der Keimbelastung wasserführender Dentaleinheiten in der Universitätsmedizin Göttingen unter besonderer Berücksichtigung von Legionella pneumophila - Bestandsaufnahme und Möglichkeiten der Keimreduzierung

“…Ihr Wachstumsoptimum liegt im Temperaturbereich zwischen 32 und 45 °C [Rogers et al 1994]. Vermehrungsfähig sind Legionellen bei Temperaturen von 25 bis 55 °C und überlebensfähig in einem umfassenden Spektrum von 0 bis 63 °C [Lode et al 1984, Wadowsky und Yee 1985, Muder et al 1986, Smith-Somerville 1991, Groothuis 1993, Horbach und Fehrenbach 1993, Lück und Helbig 1993, Rogers et al 1994, Heeg 1999].…”