Infektionen der Wirbelsäule

Value of [18F]FDG PET/CT in diagnosis and management of spondylodiscitis

“…The presence and extent or the absence of contrast enhancement are important imaging features in suspected spinal infection and are best evaluated by comparing the pre-and postcontrast MRI examinations. If an epidural abscess is detected, it is recommended to extend the sagittal MRI sequences in T2 weighting and STIR (short tau inversion recovery) to the entire spine in order not to miss so-called "skip lesions" [18,19]. Advantages and disadvantages of MRI in comparison to [ 18 F]FDG PET/CT are presented in ▶ Table 1.…”

“…One reason for the delay between diagnosis and therapy represents the initially non-specific clinical presentation of the patient requiring a high index of clinical suspicion in order to initiate the diagnostic work-up [17]. This highlights the need for clinical pathways and guidelines to optimize the diagnostic and treatment of this potential lifethreating disease [18,19]. Useful laboratory parameters that may be assessed include serum erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), white blood cell (WBC) count with differential, and blood cultures.…”

Value of [18F]FDG PET/CT in Diagnosis and Management of Spondylodiscitis

“…The presence and extent or the absence of contrast enhancement are important imaging features in suspected spinal infection and are best evaluated by comparing the pre-and postcontrast MRI examinations. If an epidural abscess is detected, it is recommended to extend the sagittal MRI se-quences in T2 weighting and STIR (short tau inversion recovery) to the entire spine in order not to miss so-called "skip lesions" [18,19]. Advantages and disadvantages of MRI in comparison to [ 18 [62].…”

“…One reason for the delay between diagnosis and therapy represents the initially non-specific clinical presentation of the patient requiring a high index of clinical suspicion in order to initiate the diagnostic work-up [17]. This highlights the need for clinical pathways and guidelines to optimize the diagnostic and treatment of this potential life-threating disease [18,19]. Useful laboratory parameters that may be assessed include serum erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), white blood cell (WBC) count with differential, and blood cultures.…”

Postoperative Wundinfektionen – Zusammenfassung und Überblick

“…Es besteht die Möglichkeit, lokale Antibiotikaträger in die Wunde einzulegen. Sollte es bereits einen Keimnachweis geben, können lokale Antibiotikaträger mit Gentamycin oder Vancomycin (bei betalaktamaseresistenten Bakterien) eingesetzt und somit die lokale Konzentration des Wirkstoffes erhöht werden [34]. Die Datenlage ist hier jedoch heterogen.…”