Infectivity of irradiated and non-irradiated metacestodes of Taenia saginata

Geerts, S.; Borchgrave, J. de; Brandt, Jef; Kumar, V.; Deken, R. De; Falla, N.; brabant, R. Van

doi:10.1016/0035-9203(92)90249-c

Cited by 3 publications

(1 citation statement)

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“…It has also been shown that low level gamma irradiation (0.3-0.6 kGy) is able to kill T. saginata cysticerci [46]. The economic loss due to bovine cysticercosis is caused by the cost of: 1. transport to an official freezing installation; 2. the freezing of the carcass; 3. a certain weight loss due to freezing (2-5%) and 4. a loss of the value of deepfrozen meat (as compared to fresh meat).…”

Section: Sanitation and Economic Lossesmentioning

confidence: 99%

The use of urban sewage sludge on pastures: the cysticercosis threat

Cabaret¹,

Geerts

Madeline³

et al. 2002

Vet. Res.

112

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-Urban sewage production is increasing and its agronomical use as a fertiliser has been advocated. Considerable defiance is prevalent in consumers and among farmers on the use of such fertilisers due to unknown pathological or environmental risks. The aim of the present review was to consider which pathological risk is major. Cysticercosis due to Taenia saginata appears to be one of the major pathological threats when sewage sludge is used to fertilise cattle pastures in temperate areas. The situation is different in Africa (Taenia solium and T. saginata are both highly prevalent) and Asia (Taenia saginata-like are prevalent). The processing of sludge and the delay between its application onto a pasture and grazing are probably major risk factors. Little data are available on the influence of processing, delay between processing and the use of sludge on the pathogenic risk. Producers and consumers will be more confident on the use of sludge if objective data are gained on risk. Most of the cases of cysticercosis (North America, United-Kingdom, Germany or Denmark) are related to poor human hygiene or accidental overflooding of sewage plants onto pastures. The standard application of sludge on pastures is apparently at low risk. This low risk does not mean that surveillance should cease since outbreaks of cysticercosis have been reported. Future investigations should concentrate on the most sustainable means of reducing risk (length of storage before use, composting, other treatments).urban sludge / parasite / cysticercosis / cattle / human Résumé -L'utilisation des boues d'épuration urbaine sur les pâturages : le risque de cysticercose. La production de boues urbaines résiduaires est en augmentation. Leur emploi agronomique comme fertilisant a été proposé. Une méfiance profonde des consommateurs ou des exploitants agricoles quant à l'emploi des boues urbaines en tant que fertilisants est réelle, qu'il s'agisse de risque pathologique ou environnemental. Le but de cette synthèse est de déterminer quel est le risque pathologique majeur. L'infestation par Taenia saginata semble être le risque le plus important en relation avec l'application 575 Vet. Res. 33 (2002) (33) 2 47427774; e-mail: cabaret@tours.inra.fr de boues d'épandages sur les pâturages bovins dans les régions tempérées. La situation est différente en Afrique (Taenia solium et T. saginata sont tous les deux très prévalents) et en Asie (les Taenia ressemblant à T. saginata ont un spectre d'hôtes herbivores assez large). Les processus de fabrication des boues et le délai entre le dépôt sur pâture et l'accès à la pâture sont sans doute des facteurs essentiels du risque. De rares données sont disponibles quant au délai et au traitement pour ce qui concerne leur pouvoir pathogène. Elles devraient être développées afin d'améliorer la confiance entre producteurs et consommateurs, sur des bases objectives. Le risque lié à l'épandage est faible comme le montrent des études aux USA, en Grande-Bretagne, Allemagne ou Danemark. La principale cause de risqu...

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Section: Sanitation and Economic Lossesmentioning

confidence: 99%

The use of urban sewage sludge on pastures: the cysticercosis threat

Cabaret¹,

Geerts

Madeline³

et al. 2002

Vet. Res.

112

View full text Add to dashboard Cite

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Apoptosis induced by gamma irradiation of Taenia solium metacestodes

et al. 2003

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Gamma irradiation of food is considered a possible approach to control food-borne diseases. In cysticercosis, previous studies have shown that irradiating (with 0.3 kGy) pork infected with Taenia solium larvae completely inhibits growth of the parasite. This study was conducted to evaluate the mechanisms that induce the effect of gamma irradiation on metacestodes of T. solium. Metacestodes were obtained from several infected pigs and irradiated with a dose of 0.3 kGy. The viability of the metacestodes was evaluated by their capacity to evaginate in vitro and in vivo development to tapeworms after they were orally infected into prednisolone-treated golden hamsters. Using the typical ladder pattern of fragmented DNA and the TdT-mediated DUTP-nick-end labeling assay, apoptosis was evaluated in metacestodes after irradiation and in the scolices and tapeworms recovered from infected hamsters at 21 days post-infection. Apoptosis was observed in the structure of scolices obtained from hamsters at 21 days post-infection with irradiated metacestodes, This study provides evidence of the existence of apoptosis in the irradiated metacestodes of T. solium and helps elucidate the possible mechanisms that are involved when gamma irradiation inhibits the normal development of the T. solium metacestode into the adult worm.

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