Infective Endocarditis in Pregnancy

Reid, Carolina; Elkayam, Uri; Rahimtoola, Shahbudin H.

doi:10.1007/978-1-4613-2415-7_106

Cited by 3 publications

(2 citation statements)

References 33 publications

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“…Fever is seen on every occasion in infective endocarditis. The heart murmurs and anemia can be seen in normal pregnant patients due to physiological effects of pregnancy on the cardiovascular system and blood volume respectively [ 7 ]. Thus, pregnant women with an unexplained fever and a cardiac murmur or a pre-existing heart condition should be monitored and investigated further.…”

Section: Discussionmentioning

confidence: 99%

Subacute Infective Endocarditis of Aortic Valve During Pregnancy

Ullah

Lakhani

Sham³

et al. 2018

Cureus

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Bacterial infective endocarditis is a rare but a life-threatening infection during pregnancy. Infective endocarditis during pregnancy is often associated with a congenital heart condition or an earlier history of rheumatic heart disease. In pregnant women with infective endocarditis, the maternal and fetal mortality rate can reach as high as 33% and 29%, respectively. In most cases, infective endocarditis runs a subacute course and involves the mitral valve, nonetheless, rarely it can involve the aortic valve as well. We are documenting a rare case of subacute infective endocarditis in a 26-year-old pregnant female with severe aortic stenosis with associated multiple systemic emboli. The patient was managed by urgent cesarean section at 35 weeks of gestation followed by aortic valve replacement; there was no maternal or fetal mortality. This case report highlights the importance of early diagnosis, and timely management of infective endocarditis in pregnant women to prevent maternal and fetal death.

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Section: Discussionmentioning

confidence: 99%

Subacute Infective Endocarditis of Aortic Valve During Pregnancy

Ullah

Lakhani

Sham³

et al. 2018

Cureus

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“…It has been postulated that CEPs are the underlying cause of up to 3% of acute coronary syndromes (ACS) [6]. Given their rarity, CEPs require a high index of suspicion by the treating clinician [8][9][10]. In this chapter, we will aim to cover the various processes and pathophysiology underlying this cause of acute coronary syndrome.…”

Section: Introductionmentioning

confidence: 99%

Coronary Embolic Phenomena: High-Impact, Low-Frequency Events

Malik¹,

Alam²,

Stawicki³

et al. 2020

Embolic Diseases - Evolving Diagnostic and Management Approaches

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Coronary embolic phenomena (CEP) are difficult to diagnose yet carry potentially devastating clinical consequences. The goal of this chapter is to outline key processes and pathophysiologic mechanisms underlying CEP, primarily in the context of acute coronary syndrome (ACS). Not surprisingly, most reported cases of CEP occur in the left coronary circulation, but some right-sided events have been reported. Overall, causes include thrombotic, septic/infectious, neoplastic, valverelated, and iatrogenic mechanisms such as air embolization. Coronary angiography remains the definitive diagnostic and therapeutic approach, with computed tomography being increasingly utilized. Transthoracic echocardiography (TTE) should be part of a routine work up for patients with suspected CEP. Holter/event monitoring for atrial fibrillation may also be indicated in patients with embolic phenomena. Clinical management includes procedural restoration of coronary blood flow, followed by appropriate anticoagulation or antiplatelet therapy, in conjunction with appropriate treatment of any arrhythmias or other associated cardiac manifestations or conditions. Timely diagnosis, based on a high index of suspicion (especially in high-risk population) may be important in improving morbidity and mortality in affected patients. Since CEPs are often underdiagnosed and may be due to a number of heterogeneous causes, the need arises for increasing provider awareness of these important phenomena, as well as for the implementation of appropriate clinical management guidelines.

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