Infective Endocarditis in a Neonate

Abstract

Bacterial endocarditis in neonates is a rare. Generally neonates who develop endocarditis have required the invasive intensive care monitoring necessary for the support and treatment of a high-risk nursery population. Neonatal Infective endocarditis is usually reported as a fatal disease. With early diagnosis and treatment we can change prognosis to better side.

Neonatal infective endocarditis in a cardiac rhabdomyoma case: A rare presentation

“…For nonbacterial thrombotic endocarditis, important risk factors are hypoxia in a neonate due to perinatal stress, low APGAR score at birth, low pH at birth, resuscitated neonate, PPHN, hyaline membrane disease. Positive blood culture, respiratory distress, new murmur, hematuria, congestive cardiac failure (CCF), fever, and central lines are seen in both types of IE [6,11]. Our patient has septicemia, persistent thrombocytopenia, required resuscitation after birth, and was culture-positive with echocardiographic evidence.…”

“…Nowadays, awareness and early detection reduce the fatality rate [8]. Congenital heart disease is found in only 8% of neonates as compared to 80% in older children and adults with IE [6,9,10].…”

“…There are no definite diagnostic criteria for neonates but still, echocardiography and blood culture are usual diagnostic tools. Thrombocytopenia is evidence of septicemia and taking longer than usual time to resolve [6]. Still, the mortality rate is 25-60% at present, it can be possibly decreased by early diagnosis and treatment with higher dose antibiotics than for sepsis [13].…”

“…Individual diseases are reported before from different countries and institutions [3,6,11,13,14]. Due to atypical and uncommon Neonatal IE in a cardiac rhabdomyoma disease of cardiac rhabdomyoma with IE in neonates, very few reports are presented in the literature.…”

“…About 50% of cardiac rhabdomyoma are associated with tuberous sclerosis and about 100 cases have been reported in different literature [4,5]. Neonatal infective endocarditis (IE) is also a rare disease but without any underlying structural heart anomalies [6].…”