Infective endocarditis in a child caused by Cardiobacterium hominis after right ventricular outflow tract reconstruction using an expanded tetrafluoroethylene conduit

Abstract

Cardiobacterium hominis, a member of the HACEK group of organisms, is a rare cause of endocarditis. We report a case of infective endocarditis caused by C. hominis in a male child who had undergone right ventricular outflow tract (RVOT) reconstruction using an expanded polytetrafluoroethylene conduit for tetralogy of Fallot with pulmonary atresia. Two days before admission, the patient suffered from exertional shortness of breath. Right ventricular hypertension was confirmed and RVOT stenosis was suspected based on the echocardiography findings. A CT scan revealed vegetation above the cusp of the conduit. An emergency operation was performed to avoid a pulmonary embolism due to large friable vegetation. C. hominis was cultured from the blood and the vegetation, prompting a diagnosis of prosthetic valve endocarditis. The patient was discharged after a 6-week course of intravenous ceftriaxone therapy.

Cardiobacterium hominis-induced acute dacryocystitis and lacrimal abscess

“…Several studies have shown the relationship of C. hominis with endocarditis. [34567] The identification of C. hominis is well established with the Vitek ® 2 compact identification system.…”

“…[2] Cardiobacterium hominis is a member of the HACEK ( Haemophilus sp., Actinobacillus actinomycetemcomitans , C. hominis , Eikenella corrodens , and Kingella kingae ) group commonly associated with endocarditits and is normally present in the oropharynx andtherespiratory tract. [3] To the best of our knowledge, we report the first case of C. hominis dacryocystitis.…”

Primary Group A Streptococcal Peritonitis in a Previously Healthy Child

“…In addition, 2 children with Fallot tetralogy and C. hominis endocarditis have been reported, one a 5-year-old male who had undergone a right ventricular reconstruction, and the other a 7-year-old female who had a Blalock-Taussing shunt operation. 4,5 Predisposing factors for C. hominis endocarditis include previous valve replacement, rheumatic heart disease, structural cardiac abnormalities and procedures such as mouth interventions and gastrointestinal endoscopy or colonoscopy. Bacteremia by C. hominis without endocarditis has been reported in 3 adults: 2 had an underlying adenocarcinoma and 1 had a pacemaker lead infection and vertebral osteomyelitis.…”

Cardiobacterium hominis infective endocarditis: A literature review

“…We searched the PubMed database to identify case reports of C. hominis IE and found 44 cases reported between January 2000 and June 2022 [1] , [6] , [7] , [8] , [9] , [10] , [11] , [12] , [13] , [14] , [15] , [16] , [17] , [18] , [19] , [20] , [21] , [22] , [23] , [24] , [25] , [26] , [27] , [28] , [29] , [30] , [31] , [32] , [33] , [34] , [35] , [36] , [37] , [38] , [39] , [40] , [41] , [42] , [43] , [44] , [45] , [46] , [47] . Herein, previously reported cases of C. hominis IE were reviewed and summarized.…”