Infective endocarditis following orthotopic heart transplantation: 10 cases and a review of the literature

Sherman-Weber, Sofia; Axelrod, Peter; Suh, Byungse; Rubin, Sally Jo; Beltramo, D.; Manacchio, J; Furukawa, Satoshi; Weber, Toni; Eisen, Howard J.; Samuel, Rafik

doi:10.1111/j.1399-3062.2004.00074.x

Cited by 91 publications

(54 citation statements)

References 10 publications

(18 reference statements)

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“…Pacjenci z nieskorygowaną siniczą wadą serca i pacjenci z wadami wrodzonymi serca (CHD) po operacjach paliatywnych ze sztucznymi połączeniami, konduitami oraz innym sztucznym materiałem [39,40]; po zabiegach operacyjnych bez rezydualnych defektów Grupa Robocza zaleca profilaktykę antybiotykową przez 6 miesięcy po operacji do czasu endotelializacji sztucznego materiału. Chociaż AHA w swoich wytycznych rekomenduje profilaktykę antybiotykową po przeszczepieniu serca u biorców, u których rozwinęły się zmiany degeneracyjne w obrębie zastawek, brakuje dowodów potwierdzających taki sposób postępowania [5,25,41], dlatego nie jest ono rekomendowane przez Grupę Roboczą ESC.…”

Section: Zagrożona Populacjaunclassified

2015 ESC Guidelines for the management of infective endocarditis

Habib¹,

Lancellotti

Antunes³

et al. 2015

Kardiol Pol

144

212

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Section: Zagrożona Populacjaunclassified

2015 ESC Guidelines for the management of infective endocarditis

Habib¹,

Lancellotti

Antunes³

et al. 2015

Kardiol Pol

144

212

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“…Their review of the literature documented only 22 cases of transplant allograft endocarditis with involvement of the right sided atrio-ventricular valve in seven (22%). It is not clear from the paper if valve surgery was attempted in this cohort or if clinical futility prevented this option (22).…”

Section: Endocarditismentioning

confidence: 99%

Tricuspid valve regurgitation after heart transplantation

Kwon¹,

Shemin²

2017

Ann. Cardiothorac. Surg.

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“…Nevertheless, the time between sampling and obtaining the results of culture may be as long as 7 to 10 days, which may be too long for the introduction of effective treatment. Moreover, the sensitivity of this method for the isolation of fungi is low (Badiee et al, 2014;Sherman-Weber et al, 2004). Candida species was detected by blood culture in 15.6%.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of semi-nested polymerase chain reaction (PCR) and mannan antigen detection compared to blood culture for diagnosis of candidemia

Al-Kasaby¹,

Kheir²,

Mefreh³

et al. 2017

Afr. J. Microbiol. Res.

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Invasive Candida infections have emerged as an important pathogen in the last decade, especially in immunocompromized patients. The aim of the present study was to evaluate the detection of Candida species in blood samples from pediatric patients with sepsis by blood culture method versus antigen detection method by enzyme linked immunosorbent assay (ELISA) and molecular method by polymerase chain reaction (PCR). This cross-sectional study was carried out on children at Mansoura University Children Hospital (MUCH) with the presence of clinical signs suggesting sepsis with absence of prior antifungal therapy. Laboratory diagnosis included blood culture, mannan antigen detection of Candida species by ELISA and semi-nested PCR. Candida species were detected by blood culture in 15.6% of the children and was detected by PCR and antigen detection in 20% for each. Candidemia was more frequently detected among patients with central venous lines (38.5%), children with Diabetes Mellitus (DM) (23.1%) and children with frequent blood transfusions (15.4%). However, these risk factors were not statistically significant. Mortality rate among children with candidemia was 42.9%. The sensitivity, specificity, and accuracy of antigen detection method by ELISA compared to culture, were 71.4, 89.5 and 86.7%, respectively. The sensitivity, specificity and accuracy of semi-nested PCR compared to culture were 85.7, 92.1 and 91.1% respectively. It can be concluded from this study that Candida species is a frequent pathogen associated with pediatric sepsis. Blood culture though is a reliable laboratory method for its diagnosis may lack sensitivity and requires prolonged time. Seminested PCR for detection of candidemia is sensitive, specific and accurate method. Mannan antigen detection by ELISA is rapid and easy; however, it may lacks specificity; it can be used as a preliminary method for screening. Further studies are recommended to detect the appropriate laboratory algorithm for early diagnosis of candidemia to start antifungal therapy appropriately.

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Infective endocarditis following orthotopic heart transplantation: 10 cases and a review of the literature

Cited by 91 publications

References 10 publications

2015 ESC Guidelines for the management of infective endocarditis

2015 ESC Guidelines for the management of infective endocarditis

Tricuspid valve regurgitation after heart transplantation

Evaluation of semi-nested polymerase chain reaction (PCR) and mannan antigen detection compared to blood culture for diagnosis of candidemia

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