Infective endocarditis

Cahill, Thomas J.; Prendergast, Bernard

doi:10.1016/s0140-6736(15)00067-7

Cited by 787 publications

(891 citation statements)

References 145 publications

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“…1,2,18 Advances in medical technology, increased indwelling intravascular device use and increased prevalence of comorbidities such as end-stage renal disease contribute to this burden. 33 Two LMIC studies reported on the site of acquisition of IE. Simsek-Yavuz et al 21 characterized 23% of IE cases as HAIE at a referral centre in Turkey, while Damasco et al 34 reported predominantly HAIE (56%) in two centres in Brazil.…”

Section: Place Of Infection Acquisitionmentioning

confidence: 99%

Infective Endocarditis in Low- and Middle-Income Countries

et al. 2017

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Key Points Staphylococcus is an increasingly important cause of IE in LMICs, and is the leading cause of IE in UMICs  RHD remains the major underlying cardiac pathology of IE in LMICs, identified in almost half of reported cases  The rate of microorganism non-identification is high, reaching up to 60% of IE cases in LMICs, and hampering diagnosis and treatment  Rates of access to surgery in UMICs for complicated IE are as high as in HICs, but remain dismal in lower-middle income countries SynopsisInfective endocarditis (IE) is a rare, life-threatening disease with a mortality rate of upto 25% and significant debilitating morbidities. Although much has been reported on contemporary IE in high income countries, conclusions on the state of IE in low and middle income countries (LMICs) are based on studies conducted before the year 2000. Furthermore, unique challenges in the diagnosis and management of IE persist in LMICs. This article is a review of IE studies conducted in LMICs documenting clinical experiences from the year 2000 to present. We present the causes of IE, management of patients with IE and the prevailing challenges in diagnosis and treatment of IE in LMICs.

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Section: Place Of Infection Acquisitionmentioning

confidence: 99%

Infective Endocarditis in Low- and Middle-Income Countries

et al. 2017

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“…Around 80%‐90% of IE cases result from staphylococcal, streptococcal, and enterococcal infection 8, 910…”

Section: Discussionmentioning

confidence: 99%

Right‐sided infective endocarditis in patients with uncorrected ventricular septal defect and patent ductus arteriosus: Two case reports

Sattwika

Hartopo

Anggrahini

et al. 2018

Clinical Case Reports

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Key Clinical MessageUncorrected left‐to‐right shunt congenital heart defect is a predisposing factor for infective endocarditis (IE), especially right‐sided IE which has different clinical manifestations and complications from left‐sided IE. Prompt diagnosis by means of transthoracic echocardiography and timely antibiotics management for IE are encouraged to prevent multiorgan failure and fatal pulmonary embolism.

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“…1 The concept that invasive dental procedures could cause IE was first suggested in 1923. 2 With the advent of antibiotics, the idea developed that antibiotic prophylaxis could be used before invasive dental procedures to reduce the risk of IE in susceptible individuals.…”

Section: Guidelines On Prophylaxis To Prevent Infective Endocarditis mentioning

confidence: 99%

Guidelines on prophylaxis to prevent infective endocarditis

et al. 2016

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Abstract:Infective endocarditis is a devastating disease with high morbidity and mortality. The link to oral bacteria has been known for many decades and has caused on going concern for dentists, patients and cardiologists. Since 2008, the UK has been out of step with the rest of the world where antibiotic prophylaxis is recommended for high-risk patients undergoing invasive dental procedures. Recent evidence that identified an increase in endocarditis incidence prompted a guideline review by NICE and the European Society for Cardiology -which produces guidance for the whole of Europe. Despite reviewing the same evidence they reached completely opposing conclusions. The resulting conflict of opinions and guidance is confusing and poses difficulties for dentists, cardiologists and their patients. Recent changes in the law on consent, however, may provide a solution to these difficulties and a more patient centred and pragmatic solution to the problems. This opinion piece examines the evidence and opposing guidance on antibiotic prophylaxis in the context of the recent changes in the law on consent and provides a framework for how patients at risk of endocarditis might be managed in practice C o n f i d e n t i a l Opinion Piece: Guidelines on Prophylaxis to Prevent Infective EndocarditisBackground:

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Infective endocarditis

Cited by 787 publications

References 145 publications

Infective Endocarditis in Low- and Middle-Income Countries

Infective Endocarditis in Low- and Middle-Income Countries

Right‐sided infective endocarditis in patients with uncorrected ventricular septal defect and patent ductus arteriosus: Two case reports

Guidelines on prophylaxis to prevent infective endocarditis

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