“…IE is known to be divided into acute and subacute forms, and the bacterium is generally isolated in subacute cases, in which fever, chills, sweats, anorexia, weight loss, and malaise are common symptoms [61]. S. mutans is detected in blood culture examinations in most cases [62][63][64][65][66][67][68][69][70], though one patient with a negative blood culture result on admission had S. mutans detected at the second examination conducted 12 h later [66]. In two other case reports, S. mutans was specified with a molecular method using broad-range PCR and sequencing techniques [69,70].…”