Infectious enteritis after intestinal transplantation: incidence, timing, and outcome

Ziring, David; Tran, Robert K.; Edelstein, Susan; McDiarmid, S. V.; Vargas, Jorge; Cortina, Galen; Gajjar, Nupoor A.; Ching, Natascha W. H.; Cherry, James D.; Krogstad, Paul; Renz, John F.; Fondevila, Constantino; Busuttil, Ronald W.; Farmer, Douglas G.

doi:10.1016/j.transproceed.2004.01.093

Cited by 49 publications

(50 citation statements)

References 5 publications

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“…Pediatric SBT recipients have an increased risk of developing non-CMV viral enteritis due to higher incidence of this type of infection in the general pediatric population (19) associated with the fact that most recipients are immunologically na€ ıve to these viruses (20). Adenovirus is considered an emerging pathogen (20), and younger recipient age has been described as a risk factor for adenovirus enteritis (21).…”

Section: Discussionmentioning

confidence: 99%

Infectious Complications Following Small Bowel Transplantation

Silva

Juan

Fernández-Caamaño

et al. 2016

American Journal of Transplantation

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Microbiological spectrum and outcome of infectious complications following small bowel transplantation (SBT) have not been thoroughly characterized. We performed a retrospective analysis of all patients undergoing SBT from 2004 to 2013 in Spain. Sixty-nine patients underwent a total of 87 SBT procedures (65 pediatric, 22 adult). The median follow-up was 867 days. Overall, 81 transplant patients (93.1%) developed 263 episodes of infection (incidence rate: 2.81 episodes per 1000 transplant-days), with no significant differences between adult and pediatric populations. Most infections were bacterial (47.5%). Despite universal prophylaxis, 22 transplant patients (25.3%) developed cytomegalovirus disease, mainly in the form of enteritis. Specifically, 54 episodes of opportunistic infection (OI) occurred in 35 transplant patients. Infection was the major cause of mortality (17 of

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Section: Discussionmentioning

confidence: 99%

Infectious Complications Following Small Bowel Transplantation

Silva

Juan

Fernández-Caamaño

et al. 2016

American Journal of Transplantation

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“…Adenovirus infection is also a relatively common complication in intestinal transplant recipients (Adeyi et al, 2008;Berho et al, 1998;Parizhskaya et al, 2001;Pinchoff et al, 2003;Ziring et al, 2005). Adenovirus was the second most common infectious cause of enteritis in this patient group following rotavirus in one study (Ziring et al, 2005).…”

Section: Prognosis Of Adenovirus Infection In the Immunocompromisedmentioning

confidence: 89%

Adenovirus Infection in the Immunocompromised Host

Tebruegge

Curtis

2009

Advances in Experimental Medicine and Biology

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“…In particular, EBV-associated enteropathy frequently occurs during intensive immunosuppressive therapy in UC patients (16,17). In addition, enteropathy that is associated with the reactivation of latent EBV infections has also been reported to occur following both allogeneic stem cell transplantation and intestinal transplantation (18,19). Therefore, immunosuppressive conditions can contribute to the development of enteropathies that are mainly associated with EBV-infected B cells.…”

Section: Discussionmentioning

confidence: 99%

Epstein-Barr Virus-associated Enteropathy as a Complication of Infectious Mononucleosis Mimicking Peripheral T-cell Lymphoma

Tamura¹,

Maruyama²,

Maeshima³

et al. 2013

Intern. Med.

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A 32-year-old man presented with a fever. A laboratory examination detected atypical lymphocytes and liver enzyme elevation. The serological tests for Epstein-Barr virus (EBV) were consistent with an acute infection pattern. Computed tomograpy showed bowel wall thickening, and colonoscopy revealed numerous ulcerations. The histological findings from the biopsy specimens from the colon were consistent with peripheral T-cell lymphoma (PTCL), and in situ hybridization detected EBER-1 in the atypical lymphocytes. Because his clinical and endoscopic abnormalities improved without medication, we diagnosed the patient with EBVassociated enteropathy. We herein report a rare case of EBV-associated enteropathy that required careful differentiation from PTCL.

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Infectious enteritis after intestinal transplantation: incidence, timing, and outcome

Cited by 49 publications

References 5 publications

Infectious Complications Following Small Bowel Transplantation

Infectious Complications Following Small Bowel Transplantation

Adenovirus Infection in the Immunocompromised Host

Epstein-Barr Virus-associated Enteropathy as a Complication of Infectious Mononucleosis Mimicking Peripheral T-cell Lymphoma

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