Infectious Diseases: Preparing for the Future

King, David A.; Peckham, Catherine; Waage, J. K.; Brownlie, Joe; Woolhouse, Mark

doi:10.1126/science.1129134

Cited by 175 publications

(132 citation statements)

References 2 publications

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“…Generally, emerging infectious diseases (EIDs) events are dominated by zoonosis (60.3% of EIDs) and the majority of these (71.8%) originate in wildlife and are increasing significantly over time (Jones et al, 2008). Similar conclusions are shown in Daszak et al (2000), Morens et al (2004), Weiss and McMichael (2004), and King et al (2006). For this specific system, several studies identify the importance of the domestic-wildlife interface in the transmission of these three pathogens, associating factors to the risk of infection to A. phagocytophilum and E. chaffeensis.…”

Section: Introductionsupporting

confidence: 69%

Infection of Anaplasma phagocytophilum and Ehrlichia spp. in Opossums and Dogs in Campeche, Mexico: The Role of Tick Infestation

2017

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In recent years, some tick-borne diseases such as anaplasmosis and ehrlichiosis became widespread worldwide, threatening the health of humans, domestic animals and wildlife. The aims of this study were to determine the presence of Anaplasma phagocytophilum, Ehrlichia canis, and Ehrlichia chaffeensis in 102 opossums (Didelphis spp.) and 44 owned free-ranging dogs in southeastern Mexico using a specific polymerase chain reaction (PCR). A. phagocytophilum was detected in opossums and dogs with a prevalence of 3 and 27%, respectively. E. canis was only present in 7% of dogs, while we didn't detect E. chaffeensis in any host. We report the first evidence of infections of A. phagocytophilum in Didelphis virginiana and D. marsupialis in Mexico. The infection rates and patterns we found of A. phagocytophilum suggest that dogs are more directly involved in the ecology of this pathogen than opossums. Despite the small prevalence found, our results are of public health concern because of the zoonotic capabilities of A. phagocytophilum, the high tick infestation rates found and because both opossums and free-ranging dogs can achieve high population densities in the region.

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Section: Introductionsupporting

confidence: 69%

Infection of Anaplasma phagocytophilum and Ehrlichia spp. in Opossums and Dogs in Campeche, Mexico: The Role of Tick Infestation

2017

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“…6 Hence as proper analysis of the epidemiological pattern of diseases helps the physicians with the necessary information and also provides the information to the policy makers and administrators for the formulation of policies to outfit the effect of the morbidity and mortality and also the outbreaks. 7 The most frequent reportable diseases in our hospital were viral fever (28.96%) followed by acute diarrheal diseases (26.52%), enteric fever (9.83%) and Malaria (8.12%). Outbreaks of Measles and Diphtheria were noted in our study.…”

Section: Discussionmentioning

confidence: 99%

Assessment and seasonal variations of communicable diseases: 3 year study

Kalyani¹,

Shankar²

2016

Int J Res Med Sci

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“…In a recent Foresight (www.foresight.gov.uk) report entitled ''Infectious Diseases: Preparing for the Future,'' eight categories of infectious diseases were identified for which improved detection systems would make a difference over the next 10-25 years (36). Of the eight categories, MelV represents categories one, three, and six: new diseases, zoonoses, and acute respiratory infections.…”

Section: Discussionmentioning

confidence: 99%

A previously unknown reovirus of bat origin is associated with an acute respiratory disease in humans

Chua

Crameri

Hyatt

et al. 2007

Proc. Natl. Acad. Sci. U.S.A.

204

259

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Respiratory infections constitute the most widespread human infectious disease, and a substantial proportion of them are caused by unknown etiological agents. Reoviruses (respiratory enteric orphan viruses) were first isolated from humans in the early 1950s and so named because they were not associated with any known disease. Here, we report a previously unknown reovirus (named ''Melaka virus'') isolated from a 39-year-old male patient in Melaka, Malaysia, who was suffering from high fever and acute respiratory disease at the time of virus isolation. Two of his family members developed similar symptoms Ϸ1 week later and had serological evidence of infection with the same virus. Epidemiological tracing revealed that the family was exposed to a bat in the house Ϸ1 week before the onset of the father's clinical symptoms. Genome sequence analysis indicated a close genetic relationship between Melaka virus and Pulau virus, a reovirus isolated in 1999 from fruit bats in Tioman Island, Malaysia. Screening of sera collected from human volunteers on the island revealed that 14 of 109 (13%) were positive for both Pulau and Melaka viruses. This is the first report of an orthoreovirus in association with acute human respiratory diseases. Melaka virus is serologically not related to the different types of mammalian reoviruses that were known to infect humans asymptomatically. These data indicate that batborne reoviruses can be transmitted to and cause clinical diseases in humans.respiratory infection ͉ zoonosis ͉ human-to-human transmission ͉ orthoreovirus ͉ Pulau virus

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Infectious Diseases: Preparing for the Future

Cited by 175 publications

References 2 publications

Infection of Anaplasma phagocytophilum and Ehrlichia spp. in Opossums and Dogs in Campeche, Mexico: The Role of Tick Infestation

Infection of Anaplasma phagocytophilum and Ehrlichia spp. in Opossums and Dogs in Campeche, Mexico: The Role of Tick Infestation

Assessment and seasonal variations of communicable diseases: 3 year study

A previously unknown reovirus of bat origin is associated with an acute respiratory disease in humans

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