Infectious Diseases

Brabb, Thea; Newsome, Denise; Burich, Andrew; Hanes, Martha A.

doi:10.1016/b978-0-12-380920-9.00023-7

Cited by 14 publications

(23 citation statements)

References 222 publications

(398 reference statements)

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“…Transmission of the disease among guinea pigs requires close contact; by aerosols, nasal secretions and fomites [5,8]. Susceptibility is greatest in young animals and incubation period was founded to be of 5-7 days [6,7].…”

Section: Pathogenymentioning

confidence: 99%

“…As guinea pigs seems to be more sensitive to the pathogen than rabbits, and rabbits are frequent asymptomatic carriers and cohabitants in homes and animal shops, it is advisable not to keep them in close contact [5]. In addition, Bb has been isolated in 18 species of mammals associated with respiratory disease, the elimination of the pathogen lasts a long time in animals and there is a high percentage of asymptomatic infections [9].…”

Section: Pathogenymentioning

confidence: 99%

“…Stillbirths, abortions, infertility and infections of the reproductive system can occur if haematonous spread of the bacteria develops; also the tympanic bullae may contain purulent exudates in affected animals due to ascending infection [1,5,6] (Figure 2,3). The incidence of Bb in a colony is usually 20% lower in laboratory animals if no action is taken, but this incidence is unknown in guinea pigs [7].…”

Section: Pathogenymentioning

confidence: 99%

“…To maintain a guinea pig colony free of Bb, it is considered that only pathogen-free animals should be introduced [5].Vaccination seems to not prevent asymptomatic carrier status because after infection in vaccinated animals the bacteria in the upper respiratory tract of some animals are isolated, although vaccination avoids disease [11,14,[17][18][19]. In pet guinea pigs the only feasible possibility of preventing the disease is vaccination.…”

Section: Vaccinesmentioning

confidence: 99%

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Bordetella Bronchiseptica Vaccines in Pet Guinea Pigs? A Review of the Literature

Gallego¹

2017

SOJVS

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Bordetella bronchiseptica causes severe respiratory disease in guinea pigs and it has been associated with stillbirths, abortions, infertility and infections of the reproductive system and tympanic bullae. Disease caused by Bordetella bronchiseptica in pet guinea pigs is mostly a poor understood disease; studies about this pathogen has been conducted mostly in laboratory guinea pigs. The objective of this review is to condense published information about the disease caused by Bordetella bronchiseptica in guinea pigs for the veterinarian who attends pet guinea pigs, with special emphasis on the prevention of this disease. The author concludes that vaccination in pet guinea pigs against Bordetella bronchiseptica needs to be considered for future studies. Received PathogenyBordetella bronchiseptica (Bb) is a gram-negative rod that has tropism for the ciliated respiratory epithelium. Infected pet guinea pigs can eliminate the bacteria, become asymptomatic carriers or develop the disease. The pet guinea pigs that develop the disease usually are attended at the veterinary clinic showing nasal and ocular discharge, respiratory sounds and dyspnea; the inappetence and lethargy indicate a poor prognosis. The diagnosis and treatment is based on deep nasal culture and antibiogram. Guinea pigs that have contact with the diseased guinea pig should be separated and occurrence of clinical signs should be monitorized at least until the diseased guinea pig has been cured. It is good practice to perform x-rays of the head and chest of the guinea pigs that are in contact with the diseased ones because a subclinical or early-stage disease can be detected [1][2][3].Bordetella bronchiseptica causes severe respiratory disease in guinea pigs, firstly described at the end of the 19th century [4] (Figure 1). Stillbirths, abortions, infertility and infections of the reproductive system can occur if haematonous spread of the bacteria develops; also the tympanic bullae may contain purulent exudates in affected animals due to ascending infection [1,5,6] (Figure 2,3). The incidence of Bb in a colony is usually 20% lower in laboratory animals if no action is taken, but this incidence is unknown in guinea pigs [7]. Disease caused by Bb in pet guinea pigs is mostly a poor understood disease because what is known of the disease is mostly by studies conducted in laboratory guinea pigs, and not in pet guinea pigs [1][2][3].

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Section: Pathogenymentioning

confidence: 99%

Section: Pathogenymentioning

confidence: 99%

Section: Pathogenymentioning

confidence: 99%

Section: Vaccinesmentioning

confidence: 99%

See 2 more Smart Citations

Bordetella Bronchiseptica Vaccines in Pet Guinea Pigs? A Review of the Literature

Gallego¹

2017

SOJVS

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“…Growth in vitro is best at 30°C but is slow to poor at 37°C, with minute, circular, pearlescent colonies present at 24 h and maximum-sized colonies apparent at 72 h. Colonies embed in the media and are surrounded variably by a zone of β-hemolysis Brabb et al, 2012). The organism is a short, gram-negative rod or coccobacillus, aerobic, motile, and non-spore-forming.…”

Section: A Bordetella Bronchisepticamentioning

confidence: 99%